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Standardized Computer-Assisted Analysis of 5-hmC Immunoreactivity in Dysplastic Nevi and Superficial Spreading Melanomas

5-Hydroxymethylcytosine (5-hmC) is an important intermediate of DNA demethylation. Hypomethylation of DNA is frequent in cancer, resulting in deregulation of 5-hmC levels in melanoma. However, the interpretation of the intensity and distribution of 5-hmC immunoreactivity is not very standardized, wh...

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Detalles Bibliográficos
Autores principales: Koch, Elias A. T., Berking, Carola, Erber, Ramona, Erdmann, Michael, Kiesewetter, Franklin, Schliep, Stefan, Heppt, Markus V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572721/
https://www.ncbi.nlm.nih.gov/pubmed/37834158
http://dx.doi.org/10.3390/ijms241914711