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Standardized Computer-Assisted Analysis of 5-hmC Immunoreactivity in Dysplastic Nevi and Superficial Spreading Melanomas
5-Hydroxymethylcytosine (5-hmC) is an important intermediate of DNA demethylation. Hypomethylation of DNA is frequent in cancer, resulting in deregulation of 5-hmC levels in melanoma. However, the interpretation of the intensity and distribution of 5-hmC immunoreactivity is not very standardized, wh...
Autores principales: | Koch, Elias A. T., Berking, Carola, Erber, Ramona, Erdmann, Michael, Kiesewetter, Franklin, Schliep, Stefan, Heppt, Markus V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572721/ https://www.ncbi.nlm.nih.gov/pubmed/37834158 http://dx.doi.org/10.3390/ijms241914711 |
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