Selective ROCK Inhibitor Enhances Blood Flow Recovery after Hindlimb Ischemia

The impairment in microvascular network formation could delay the restoration of blood flow after acute limb ischemia. A high-content screen of a GSK-published kinase inhibitor library identified a set of ROCK inhibitor hits enhancing endothelial network formation. Subsequent kinase activity profili...

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Detalles Bibliográficos
Autores principales: Fayed, Hend Salah, Bakleh, Mouayad Zuheir, Ashraf, Jasni Viralippurath, Howarth, Alison, Ebner, Daniel, Al Haj Zen, Ayman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572734/
https://www.ncbi.nlm.nih.gov/pubmed/37833857
http://dx.doi.org/10.3390/ijms241914410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572734/
https://www.ncbi.nlm.nih.gov/pubmed/37833857
http://dx.doi.org/10.3390/ijms241914410

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