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Aneurysmal Bone Cyst of the Pelvis in Children and Adolescents: Effectiveness of Surgical Treatment with Curettage, Cryotherapy and Bone Grafting

Background: Aneurysmal bone cysts (ABCs) are benign but locally aggressive cystic lesions of the bone. Pelvic ABCs are extremely rare and hard to treat due to their high risk of local recurrence and the tough access to pelvic bones. Methods: In this retrospective study, we evaluated pediatric cases...

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Autores principales: Andreani, Lorenzo, Ipponi, Edoardo, Serrano, Elena, De Franco, Silvia, Cordoni, Martina, Bechini, Elena, D’Arienzo, Antonio, Parchi, Paolo Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572795/
https://www.ncbi.nlm.nih.gov/pubmed/37830695
http://dx.doi.org/10.3390/healthcare11192658
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author Andreani, Lorenzo
Ipponi, Edoardo
Serrano, Elena
De Franco, Silvia
Cordoni, Martina
Bechini, Elena
D’Arienzo, Antonio
Parchi, Paolo Domenico
author_facet Andreani, Lorenzo
Ipponi, Edoardo
Serrano, Elena
De Franco, Silvia
Cordoni, Martina
Bechini, Elena
D’Arienzo, Antonio
Parchi, Paolo Domenico
author_sort Andreani, Lorenzo
collection PubMed
description Background: Aneurysmal bone cysts (ABCs) are benign but locally aggressive cystic lesions of the bone. Pelvic ABCs are extremely rare and hard to treat due to their high risk of local recurrence and the tough access to pelvic bones. Methods: In this retrospective study, we evaluated pediatric cases with pelvic ABC treated with curettage, cryotherapy and bone grafting treated in our institution between 2016 and 2022. Complications were recorded, as well as local recurrences. Patients’ post-operative functionality was assessed with the MSTS score. Results: Fourteen consecutive cases were included in our study. Their mean age at surgery was 13.5 years. The mean lesion size was 55 mm. The mean follow-up was 38 months. Two cases (11.8%) had local recurrences, which were successfully treated with further curettage. At their latest FU, 13 cases were continuously disease free (CDF), and one had no evidence of disease (NED). Only one case had a post-operative compilation (wound dehiscence). Patients’ mean post-operative MSTS score was 29.6. Conclusions: Pelvic ABCs are a challenge, even for the most experienced orthopedic surgeon. Our study suggests that the association of an accurate curettage, intraoperative cryotherapy and bone grafting can be a reliable and effective therapeutic option for large-sized ABCs of the pelvis.
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spelling pubmed-105727952023-10-14 Aneurysmal Bone Cyst of the Pelvis in Children and Adolescents: Effectiveness of Surgical Treatment with Curettage, Cryotherapy and Bone Grafting Andreani, Lorenzo Ipponi, Edoardo Serrano, Elena De Franco, Silvia Cordoni, Martina Bechini, Elena D’Arienzo, Antonio Parchi, Paolo Domenico Healthcare (Basel) Article Background: Aneurysmal bone cysts (ABCs) are benign but locally aggressive cystic lesions of the bone. Pelvic ABCs are extremely rare and hard to treat due to their high risk of local recurrence and the tough access to pelvic bones. Methods: In this retrospective study, we evaluated pediatric cases with pelvic ABC treated with curettage, cryotherapy and bone grafting treated in our institution between 2016 and 2022. Complications were recorded, as well as local recurrences. Patients’ post-operative functionality was assessed with the MSTS score. Results: Fourteen consecutive cases were included in our study. Their mean age at surgery was 13.5 years. The mean lesion size was 55 mm. The mean follow-up was 38 months. Two cases (11.8%) had local recurrences, which were successfully treated with further curettage. At their latest FU, 13 cases were continuously disease free (CDF), and one had no evidence of disease (NED). Only one case had a post-operative compilation (wound dehiscence). Patients’ mean post-operative MSTS score was 29.6. Conclusions: Pelvic ABCs are a challenge, even for the most experienced orthopedic surgeon. Our study suggests that the association of an accurate curettage, intraoperative cryotherapy and bone grafting can be a reliable and effective therapeutic option for large-sized ABCs of the pelvis. MDPI 2023-09-30 /pmc/articles/PMC10572795/ /pubmed/37830695 http://dx.doi.org/10.3390/healthcare11192658 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Andreani, Lorenzo
Ipponi, Edoardo
Serrano, Elena
De Franco, Silvia
Cordoni, Martina
Bechini, Elena
D’Arienzo, Antonio
Parchi, Paolo Domenico
Aneurysmal Bone Cyst of the Pelvis in Children and Adolescents: Effectiveness of Surgical Treatment with Curettage, Cryotherapy and Bone Grafting
title Aneurysmal Bone Cyst of the Pelvis in Children and Adolescents: Effectiveness of Surgical Treatment with Curettage, Cryotherapy and Bone Grafting
title_full Aneurysmal Bone Cyst of the Pelvis in Children and Adolescents: Effectiveness of Surgical Treatment with Curettage, Cryotherapy and Bone Grafting
title_fullStr Aneurysmal Bone Cyst of the Pelvis in Children and Adolescents: Effectiveness of Surgical Treatment with Curettage, Cryotherapy and Bone Grafting
title_full_unstemmed Aneurysmal Bone Cyst of the Pelvis in Children and Adolescents: Effectiveness of Surgical Treatment with Curettage, Cryotherapy and Bone Grafting
title_short Aneurysmal Bone Cyst of the Pelvis in Children and Adolescents: Effectiveness of Surgical Treatment with Curettage, Cryotherapy and Bone Grafting
title_sort aneurysmal bone cyst of the pelvis in children and adolescents: effectiveness of surgical treatment with curettage, cryotherapy and bone grafting
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572795/
https://www.ncbi.nlm.nih.gov/pubmed/37830695
http://dx.doi.org/10.3390/healthcare11192658
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