Cargando…

Mitochondrial Metabolism in the Spotlight: Maintaining Balanced RNAP III Activity Ensures Cellular Homeostasis

RNA polymerase III (RNAP III) holoenzyme activity and the processing of its products have been linked to several metabolic dysfunctions in lower and higher eukaryotes. Alterations in the activity of RNAP III-driven synthesis of non-coding RNA cause extensive changes in glucose metabolism. Increased...

Descripción completa

Detalles Bibliográficos
Autores principales:	Szatkowska, Roza, Furmanek, Emil, Kierzek, Andrzej M., Ludwig, Christian, Adamczyk, Malgorzata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572830/ https://www.ncbi.nlm.nih.gov/pubmed/37834211 http://dx.doi.org/10.3390/ijms241914763

Ejemplares similares

Glycolytic flux in Saccharomyces cerevisiae is dependent on RNA polymerase III and its negative regulator Maf1
por: Szatkowska, Roza, et al.
Publicado: (2019)

Low RNA Polymerase III activity results in up regulation of HXT2 glucose transporter independently of glucose signaling and despite changing environment
por: Adamczyk, Malgorzata, et al.
Publicado: (2017)

Cellular sequestrases maintain basal Hsp70 capacity ensuring balanced proteostasis
por: Ho, Chi-ting, et al.
Publicado: (2019)

Regulation of Eukaryotic RNAPs Activities by Phosphorylation
por: González-Jiménez, Araceli, et al.
Publicado: (2021)

Yeast Sirtuin Family Members Maintain Transcription Homeostasis to Ensure Genome Stability
por: Feldman, Jessica L., et al.
Publicado: (2019)

Identification of tri-phosphatase activity in the biogenesis of retroviral microRNAs and RNAP III-generated shRNAs
por: Burke, James M., et al.
Publicado: (2014)

Genome-wide mapping of the distribution of CarD, RNAP σ(A), and RNAP β on the Mycobacterium smegmatis chromosome using chromatin immunoprecipitation sequencing
por: Landick, Robert, et al.
Publicado: (2014)

Why Are tRNAs Overproduced in the Absence of Maf1, a Negative Regulator of RNAP III, Not Fully Functional?
por: Boguta, Magdalena
Publicado: (2015)

Polarity signaling ensures epidermal homeostasis by coupling cellular mechanics and genomic integrity
por: Dias Gomes, Martim, et al.
Publicado: (2019)

ChIP-exo interrogation of Crp, DNA, and RNAP holoenzyme interactions
por: Latif, Haythem, et al.
Publicado: (2018)

The functional importance of VCP to maintaining cellular protein homeostasis
por: Ahlstedt, Brittany A., et al.
Publicado: (2022)

RNAP II CTD tyrosine 1 performs diverse functions in vertebrate cells
por: Hsin, Jing-Ping, et al.
Publicado: (2014)

Yeast mitochondrial RNAP conformational changes are regulated by interactions with the mitochondrial transcription factor
por: Drakulic, Srdja, et al.
Publicado: (2014)

RNAP-II Molecules Participate in the Anchoring of the ORC to rDNA Replication Origins
por: Mayan, Maria D.
Publicado: (2013)

Primary microRNA processing is functionally coupled to RNAP II transcription in vitro
por: Yin, Shanye, et al.
Publicado: (2015)

Dynamics of promoter bivalency and RNAP II pausing in mouse stem and differentiated cells
por: Mantsoki, Anna, et al.
Publicado: (2018)

Evolutionary Invariant of the Structure of DNA Double Helix in RNAP II Core Promoters
por: Melikhova, Anastasia V., et al.
Publicado: (2022)

ESCRT-III and ER–PM contacts maintain lipid homeostasis
por: Jorgensen, Jeff R., et al.
Publicado: (2020)

Hypoxia Helps Maintain Nucleus Pulposus Homeostasis by Balancing Autophagy and Apoptosis
por: Kim, Han-Jun, et al.
Publicado: (2020)

The Balance between Differentiation and Terminal Differentiation Maintains Oral Epithelial Homeostasis
por: Bai, Yuchen, et al.
Publicado: (2021)

Maintaining Golgi Homeostasis: A Balancing Act of Two Proteolytic Pathways
por: Benyair, Ron, et al.
Publicado: (2022)

Hypothalamic Inflammation and Energy Balance Disruptions: Spotlight on Chemokines
por: Le Thuc, Ophélia, et al.
Publicado: (2017)

TraR, a Homolog of a RNAP Secondary Channel Interactor, Modulates Transcription
por: Blankschien, Matthew D., et al.
Publicado: (2009)

The Non-Canonical CTD of RNAP-II Is Essential for Productive RNA Synthesis in Trypanosoma brucei
por: Das, Anish, et al.
Publicado: (2009)

The transcription factor network of E. coli steers global responses to shifts in RNAP concentration
por: L.B. Almeida, Bilena, et al.
Publicado: (2022)

A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II
por: Liu, Yanli, et al.
Publicado: (2022)

Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis
por: Wojciechowski, Sara, et al.
Publicado: (2007)

Exosomes maintain cellular homeostasis by excreting harmful DNA from cells
por: Takahashi, Akiko, et al.
Publicado: (2017)

Ensuring Well-Being in a Postpandemic World: Ensuring our Specialty Maintains its Resilience
por: Fleisher, Lee A.
Publicado: (2022)

Combined SPT and FCS methods reveal a mechanism of RNAP II oversampling in cell nuclei
por: Fournier, Marie, et al.
Publicado: (2023)

Towards T7 RNA polymerase (T7RNAP)-based expression system in yeast: challenges and opportunities
por: Sáez Moreno, David, et al.
Publicado: (2023)

GANT-61 induces cell cycle resting and autophagy by down-regulating RNAP III signal pathway and tRNA-Gly-CCC synthesis to combate chondrosarcoma
por: Sun, Yifeng, et al.
Publicado: (2023)

Astrocytes Maintain Glutamate Homeostasis in the CNS by Controlling the Balance between Glutamate Uptake and Release
por: Mahmoud, Shaimaa, et al.
Publicado: (2019)

Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding
por: He, Dingwei, et al.
Publicado: (2022)

Synthetic evolution of herbicide resistance using a T7 RNAP–based random DNA base editor
por: Butt, Haroon, et al.
Publicado: (2022)

Pancreatic Cancer and Cellular Senescence: Tumor Microenvironment under the Spotlight
por: Cortesi, Michela, et al.
Publicado: (2021)

Attitude Trajectory Optimization to Ensure Balance Hexapod Locomotion
por: Chen, Chen, et al.
Publicado: (2020)

AMPK directly inhibits NDPK through a phosphoserine switch to maintain cellular homeostasis
por: Onyenwoke, Rob U., et al.
Publicado: (2012)

Publisher Correction: Exosomes maintain cellular homeostasis by excreting harmful DNA from cells
por: Takahashi, Akiko, et al.
Publicado: (2018)

Nucleotide-induced asymmetry within ATPase activator ring drives σ54–RNAP interaction and ATP hydrolysis
por: Sysoeva, Tatyana A., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_i5i4s660m4k2lkfr1up2pe3qjm