Single-Cell Profiling of Cells in the Lung of a Patient with Chronic Hypersensitivity Pneumonitis Reveals Inflammatory Niche with Abundant CD39+ T Cells with Functional ATPase Phenotype: A Case Study

This study investigated immune cell characteristics in chronic hypersensitivity pneumonitis (HP), focusing on CD39-expressing cells’ impact on inflammation and tissue remodelling. Lung tissue from an HP patient was analysed using single-cell transcriptomics, flow cytometry, and gene expression profi...

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Detalles Bibliográficos
Autores principales: de Silva, Tharushi Ayanthika, Apte, Simon, Voisey, Joanne, Spann, Kirsten, Tan, Maxine, Divithotawela, Chandima, Chambers, Daniel, O’Sullivan, Brendan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572861/
https://www.ncbi.nlm.nih.gov/pubmed/37833889
http://dx.doi.org/10.3390/ijms241914442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572861/
https://www.ncbi.nlm.nih.gov/pubmed/37833889
http://dx.doi.org/10.3390/ijms241914442

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