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Evaluation of the Potential Impact of In Silico Humanization on V(H)H Dynamics

Camelids have the peculiarity of having classical antibodies composed of heavy and light chains as well as single-chain antibodies. They have lost their light chains and one heavy-chain domain. This evolutionary feature means that their terminal heavy-chain domain, VH, called V(H)H here, has no part...

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Detalles Bibliográficos
Autores principales: Martins, Carla, Diharce, Julien, Nadaradjane, Aravindan Arun, de Brevern, Alexandre G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572902/
https://www.ncbi.nlm.nih.gov/pubmed/37834033
http://dx.doi.org/10.3390/ijms241914586

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