Cargando…
Metabolomic Signatures of Alzheimer’s Disease Indicate Brain Region-Specific Neurodegenerative Progression
Pathological mechanisms contributing to Alzheimer’s disease (AD) are still elusive. Here, we identified the metabolic signatures of AD in human post-mortem brains. Using (1)H NMR spectroscopy and an untargeted metabolomics approach, we identified (1) metabolomic profiles of AD and age-matched health...
Autores principales: | Ambeskovic, Mirela, Hopkins, Giselle, Hoover, Tanzi, Joseph, Jeffrey T., Montina, Tony, Metz, Gerlinde A. S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573054/ https://www.ncbi.nlm.nih.gov/pubmed/37834217 http://dx.doi.org/10.3390/ijms241914769 |
Ejemplares similares
-
Ancestral stress programs sex-specific biological aging trajectories and non-communicable disease risk
por: Ambeskovic, Mirela, et al.
Publicado: (2020) -
Urinary metabolomic signatures as indicators of injury severity following traumatic brain injury: A pilot study
por: Bykowski, Elani A., et al.
Publicado: (2021) -
Trans- and Multigenerational Maternal Social Isolation Stress Programs the Blood Plasma Metabolome in the F3 Generation
por: Heynen, Joshua P., et al.
Publicado: (2022) -
Ancestral Stress Alters Lifetime Mental Health Trajectories and Cortical Neuromorphology via Epigenetic Regulation
por: Ambeskovic, Mirela, et al.
Publicado: (2019) -
Prenatal Maternal Stress from a Natural Disaster Alters Urinary Metabolomic Profiles in Project Ice Storm Participants
por: Paxman, Eric J., et al.
Publicado: (2018)