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The Effect of Polymer Blends on the In Vitro Release/Degradation and Pharmacokinetics of Moxidectin-Loaded PLGA Microspheres

To investigate the effect of polymer blends on the in vitro release/degradation and pharmacokinetics of moxidectin-loaded PLGA microspheres (MOX-MS), four formulations (F1, F2, F3 and F4) were prepared using the O/W emulsion solvent evaporation method by blending high (75/25, 75 kDa) and low (50/50,...

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Detalles Bibliográficos
Autores principales: Zhang, Hongjuan, Yang, Zhen, Wu, Di, Hao, Baocheng, Liu, Yu, Wang, Xuehong, Pu, Wanxia, Yi, Yunpeng, Shang, Ruofeng, Wang, Shengyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573114/
https://www.ncbi.nlm.nih.gov/pubmed/37834176
http://dx.doi.org/10.3390/ijms241914729