Cargando…

Diabetes Mellitus Is a Possible Risk Factor for the Development of Trochanteric Bursitis—A Large-Scale Population-Based Study

Background: Trochanteric Bursitis (TB) is a common reason to seek primary care, previously shown to be associated with female gender and obesity. Diabetes mellitus (DM) has several musculoskeletal manifestations, but was never found to be associated with TB. Purpose: To explore the association betwe...

Descripción completa

Detalles Bibliográficos
Autores principales: Kadar, Assaf, Itzikovitch, Ron, Warschawski, Yaniv, Morgan, Samuel, Shemesh, Shai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573166/
https://www.ncbi.nlm.nih.gov/pubmed/37834819
http://dx.doi.org/10.3390/jcm12196174
_version_ 1785120398947385344
author Kadar, Assaf
Itzikovitch, Ron
Warschawski, Yaniv
Morgan, Samuel
Shemesh, Shai
author_facet Kadar, Assaf
Itzikovitch, Ron
Warschawski, Yaniv
Morgan, Samuel
Shemesh, Shai
author_sort Kadar, Assaf
collection PubMed
description Background: Trochanteric Bursitis (TB) is a common reason to seek primary care, previously shown to be associated with female gender and obesity. Diabetes mellitus (DM) has several musculoskeletal manifestations, but was never found to be associated with TB. Purpose: To explore the association between DM and TB, based on a large database. The secondary aim was to explore the influence of gender and insulin usage on the occurrence of TB. Study design: cross-sectional study. Methods: A population-based cohort consisting of 60,610 patients (55,428 without DM and 5182 with DM), of whom 5418 were diagnosed with TB. A logistic regression model was applied to estimate propensity scores. Results: The odds of individuals with DM being diagnosed with TB were 55.8% higher compared to the odds of patients without DM (OR: 1.558, 95% CI: [1.429, 1.70], p < 0.0001). We found that insulin users had a lower risk of TB than patients not using insulin (log-rank p < 0.0001). Females are 3.3 times more likely to have TB than males (RR: 3.337, 95% CI: [3.115, 3.584], p < 0.0001). Conclusions: DM is a risk factor for developing TB. Insulin had a protective effect against TB, suggesting that better glycemic control might prevent this painful infliction.
format Online
Article
Text
id pubmed-10573166
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-105731662023-10-14 Diabetes Mellitus Is a Possible Risk Factor for the Development of Trochanteric Bursitis—A Large-Scale Population-Based Study Kadar, Assaf Itzikovitch, Ron Warschawski, Yaniv Morgan, Samuel Shemesh, Shai J Clin Med Article Background: Trochanteric Bursitis (TB) is a common reason to seek primary care, previously shown to be associated with female gender and obesity. Diabetes mellitus (DM) has several musculoskeletal manifestations, but was never found to be associated with TB. Purpose: To explore the association between DM and TB, based on a large database. The secondary aim was to explore the influence of gender and insulin usage on the occurrence of TB. Study design: cross-sectional study. Methods: A population-based cohort consisting of 60,610 patients (55,428 without DM and 5182 with DM), of whom 5418 were diagnosed with TB. A logistic regression model was applied to estimate propensity scores. Results: The odds of individuals with DM being diagnosed with TB were 55.8% higher compared to the odds of patients without DM (OR: 1.558, 95% CI: [1.429, 1.70], p < 0.0001). We found that insulin users had a lower risk of TB than patients not using insulin (log-rank p < 0.0001). Females are 3.3 times more likely to have TB than males (RR: 3.337, 95% CI: [3.115, 3.584], p < 0.0001). Conclusions: DM is a risk factor for developing TB. Insulin had a protective effect against TB, suggesting that better glycemic control might prevent this painful infliction. MDPI 2023-09-24 /pmc/articles/PMC10573166/ /pubmed/37834819 http://dx.doi.org/10.3390/jcm12196174 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kadar, Assaf
Itzikovitch, Ron
Warschawski, Yaniv
Morgan, Samuel
Shemesh, Shai
Diabetes Mellitus Is a Possible Risk Factor for the Development of Trochanteric Bursitis—A Large-Scale Population-Based Study
title Diabetes Mellitus Is a Possible Risk Factor for the Development of Trochanteric Bursitis—A Large-Scale Population-Based Study
title_full Diabetes Mellitus Is a Possible Risk Factor for the Development of Trochanteric Bursitis—A Large-Scale Population-Based Study
title_fullStr Diabetes Mellitus Is a Possible Risk Factor for the Development of Trochanteric Bursitis—A Large-Scale Population-Based Study
title_full_unstemmed Diabetes Mellitus Is a Possible Risk Factor for the Development of Trochanteric Bursitis—A Large-Scale Population-Based Study
title_short Diabetes Mellitus Is a Possible Risk Factor for the Development of Trochanteric Bursitis—A Large-Scale Population-Based Study
title_sort diabetes mellitus is a possible risk factor for the development of trochanteric bursitis—a large-scale population-based study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573166/
https://www.ncbi.nlm.nih.gov/pubmed/37834819
http://dx.doi.org/10.3390/jcm12196174
work_keys_str_mv AT kadarassaf diabetesmellitusisapossibleriskfactorforthedevelopmentoftrochantericbursitisalargescalepopulationbasedstudy
AT itzikovitchron diabetesmellitusisapossibleriskfactorforthedevelopmentoftrochantericbursitisalargescalepopulationbasedstudy
AT warschawskiyaniv diabetesmellitusisapossibleriskfactorforthedevelopmentoftrochantericbursitisalargescalepopulationbasedstudy
AT morgansamuel diabetesmellitusisapossibleriskfactorforthedevelopmentoftrochantericbursitisalargescalepopulationbasedstudy
AT shemeshshai diabetesmellitusisapossibleriskfactorforthedevelopmentoftrochantericbursitisalargescalepopulationbasedstudy