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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Protein S1 Induces Methylglyoxal-Derived Hydroimidazolone/Receptor for Advanced Glycation End Products (MG-H1/RAGE) Activation to Promote Inflammation in Human Bronchial BEAS-2B Cells
The pathogenesis of coronavirus disease 2019 (COVID-19) is associated with a hyperinflammatory response. The mechanisms of SARS-CoV-2-induced inflammation are scantly known. Methylglyoxal (MG) is a glycolysis-derived byproduct endowed with a potent glycating action, leading to the formation of advan...
Autores principales: | Manfredelli, Dominga, Pariano, Marilena, Costantini, Claudio, Graziani, Alessandro, Bozza, Silvia, Romani, Luigina, Puccetti, Paolo, Talesa, Vincenzo Nicola, Antognelli, Cinzia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573269/ https://www.ncbi.nlm.nih.gov/pubmed/37834316 http://dx.doi.org/10.3390/ijms241914868 |
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