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Double-stemmed and split structural variants of fluorescent RNA Mango aptamers

Aptamers with fluorogenic ligands are emerging as useful tools to quantify and track RNA molecules. The RNA Mango family of aptamers have a useful combination of tight ligand binding, bright fluorescence, and small size. However, the simple structure of these aptamers, with a single base-paired stem...

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Detalles Bibliográficos
Autores principales: Herrera-Gutierrez, Jeremy, Burden, Steven J., Kobernat, Sarah E., Shults, Nicholas H., Smith, Mark, Fologea, Daniel, Hayden, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573287/
https://www.ncbi.nlm.nih.gov/pubmed/37268327
http://dx.doi.org/10.1261/rna.079651.123