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Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA
DEAD-box RNA helicases are implicated in most aspects of RNA biology, where these enzymes unwind short RNA duplexes in an ATP-dependent manner. During the central step of the unwinding cycle, the two domains of the helicase core form a distinct closed conformation that destabilizes the RNA duplex, w...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573307/ https://www.ncbi.nlm.nih.gov/pubmed/37221012 http://dx.doi.org/10.1261/rna.079582.123 |