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CRISPR/dCas9 Tools: Epigenetic Mechanism and Application in Gene Transcriptional Regulation
CRISPR/Cas9-mediated cleavage of DNA, which depends on the endonuclease activity of Cas9, has been widely used for gene editing due to its excellent programmability and specificity. However, the changes to the DNA sequence that are mediated by CRISPR/Cas9 affect the structures and stability of the g...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573330/ https://www.ncbi.nlm.nih.gov/pubmed/37834313 http://dx.doi.org/10.3390/ijms241914865 |