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Pancreatic Cancer-Derived Exosomal miR-Let-7b-5p Stimulates Insulin Resistance in Skeletal Muscle Cells Through RNF20/STAT3/FOXO1 Axis Regulation

BACKGROUND: Cancers trigger systemic metabolic disorders usually associated with glucose intolerance, which is an initially apparent phenomenon. One of the features of pancreatic cancer (PC) metabolic reprogramming is the crosstalk between PC and peripheral tissues (skeletal muscle and adipose tissu...

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Detalles Bibliográficos
Autores principales: Wang, Lantian, Li, Xiawei, Wu, Jian, Tang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573399/
https://www.ncbi.nlm.nih.gov/pubmed/37842335
http://dx.doi.org/10.2147/DMSO.S430443

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