Aβ1-42 Accumulation Accompanies Changed Expression of Ly6/uPAR Proteins, Dysregulation of the Cholinergic System, and Degeneration of Astrocytes in the Cerebellum of Mouse Model of Early Alzheimer Disease

Alzheimer disease (AD) is a widespread neurodegenerative disease characterized by the accumulation of oligomeric toxic forms of β-amyloid (Aβ1-42) and dysfunction of the cholinergic system in the different brain regions. However, the exact mechanisms of AD pathogenesis and the role of the nicotinic...

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Detalles Bibliográficos
Autores principales: Bychkov, Maxim L., Isaev, Aizek B., Andreev-Andrievskiy, Alexander A., Petrov, Konstantin, Paramonov, Alexander S., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573428/
https://www.ncbi.nlm.nih.gov/pubmed/37834299
http://dx.doi.org/10.3390/ijms241914852

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