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Different Types of Vasculitis Complicated by Heparin-Induced Thrombocytopenia—Analysis of Four Cases and Literature Review

Vasculitis and HIT have different etiologies, although both involve autoimmune mechanisms. Treatment of vasculitis often requires the use of an anticoagulant such as heparin, which can lead to the development of HIT and subsequent life-threatening complications. The analysis covered patients hospita...

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Autores principales: Rytel, Adam, Nowak, Mateusz, Kukawska-Rytel, Monika, Morawiec, Katarzyna, Niemczyk, Stanisław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573553/
https://www.ncbi.nlm.nih.gov/pubmed/37834820
http://dx.doi.org/10.3390/jcm12196176
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author Rytel, Adam
Nowak, Mateusz
Kukawska-Rytel, Monika
Morawiec, Katarzyna
Niemczyk, Stanisław
author_facet Rytel, Adam
Nowak, Mateusz
Kukawska-Rytel, Monika
Morawiec, Katarzyna
Niemczyk, Stanisław
author_sort Rytel, Adam
collection PubMed
description Vasculitis and HIT have different etiologies, although both involve autoimmune mechanisms. Treatment of vasculitis often requires the use of an anticoagulant such as heparin, which can lead to the development of HIT and subsequent life-threatening complications. The analysis covered patients hospitalized in the Department of Internal Medicine, Nephrology and Dialysis in the period from September 2020 to March 2023. After analyzing the data, we selected four patients in whom vasculitis treatment was complicated by HIT. These included two patients with ANCA vasculitis and two patients with anti-GBM disease. We also described similar cases reported in the literature.
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spelling pubmed-105735532023-10-14 Different Types of Vasculitis Complicated by Heparin-Induced Thrombocytopenia—Analysis of Four Cases and Literature Review Rytel, Adam Nowak, Mateusz Kukawska-Rytel, Monika Morawiec, Katarzyna Niemczyk, Stanisław J Clin Med Review Vasculitis and HIT have different etiologies, although both involve autoimmune mechanisms. Treatment of vasculitis often requires the use of an anticoagulant such as heparin, which can lead to the development of HIT and subsequent life-threatening complications. The analysis covered patients hospitalized in the Department of Internal Medicine, Nephrology and Dialysis in the period from September 2020 to March 2023. After analyzing the data, we selected four patients in whom vasculitis treatment was complicated by HIT. These included two patients with ANCA vasculitis and two patients with anti-GBM disease. We also described similar cases reported in the literature. MDPI 2023-09-24 /pmc/articles/PMC10573553/ /pubmed/37834820 http://dx.doi.org/10.3390/jcm12196176 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Rytel, Adam
Nowak, Mateusz
Kukawska-Rytel, Monika
Morawiec, Katarzyna
Niemczyk, Stanisław
Different Types of Vasculitis Complicated by Heparin-Induced Thrombocytopenia—Analysis of Four Cases and Literature Review
title Different Types of Vasculitis Complicated by Heparin-Induced Thrombocytopenia—Analysis of Four Cases and Literature Review
title_full Different Types of Vasculitis Complicated by Heparin-Induced Thrombocytopenia—Analysis of Four Cases and Literature Review
title_fullStr Different Types of Vasculitis Complicated by Heparin-Induced Thrombocytopenia—Analysis of Four Cases and Literature Review
title_full_unstemmed Different Types of Vasculitis Complicated by Heparin-Induced Thrombocytopenia—Analysis of Four Cases and Literature Review
title_short Different Types of Vasculitis Complicated by Heparin-Induced Thrombocytopenia—Analysis of Four Cases and Literature Review
title_sort different types of vasculitis complicated by heparin-induced thrombocytopenia—analysis of four cases and literature review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573553/
https://www.ncbi.nlm.nih.gov/pubmed/37834820
http://dx.doi.org/10.3390/jcm12196176
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