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Enrichment of Activated Fibroblasts as a Potential Biomarker for a Non-Durable Response to Anti-Tumor Necrosis Factor Therapy in Patients with Crohn’s Disease

We investigated whether the response to anti-tumor necrosis factor (anti-TNF) treatment varied according to inflammatory tissue characteristics in Crohn’s disease (CD). Bulk RNA sequencing (RNA-seq) data were obtained from inflamed and non-inflamed tissues from 170 patients with CD. The samples were...

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Detalles Bibliográficos
Autores principales: Park, Soo-Kyung, Lee, Gi-Young, Kim, Sangsoo, Lee, Chil-Woo, Choi, Chang-Hwan, Kang, Sang-Bum, Kim, Tae-Oh, Chun, Jaeyoung, Cha, Jae-Myung, Im, Jong-Pil, Ahn, Kwang-Sung, Kim, Seon-Young, Kim, Min-Suk, Lee, Chang-Kyun, Park, Dong-Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573580/
https://www.ncbi.nlm.nih.gov/pubmed/37834250
http://dx.doi.org/10.3390/ijms241914799