Cargando…

Evaluation of Tropicamide–Phenylephrine Mydriatic Eye Drop Instillation on Choroidal Thickness

The purpose of this study is to evaluate choroidal thickness (ChT) at the subfoveal and peripheral level after the instillation of 0.5% tropicamide + 10% phenylephrine 9 hydrochloride eye drops by using OCT scans in enhanced depth image (EDI) mode. In total, 53 patients (30 males and 23 females) wer...

Descripción completa

Detalles Bibliográficos
Autores principales: Gioia, Marco, De Bernardo, Maddalena, Pagliarulo, Sergio, Cione, Ferdinando, Mottola, Francesco Ferdinando, La Marca, Aniello, De Pascale, Ilaria, Albano, Giovanni, Rosa, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573589/
https://www.ncbi.nlm.nih.gov/pubmed/37834998
http://dx.doi.org/10.3390/jcm12196355
_version_ 1785120499459686400
author Gioia, Marco
De Bernardo, Maddalena
Pagliarulo, Sergio
Cione, Ferdinando
Mottola, Francesco Ferdinando
La Marca, Aniello
De Pascale, Ilaria
Albano, Giovanni
Rosa, Nicola
author_facet Gioia, Marco
De Bernardo, Maddalena
Pagliarulo, Sergio
Cione, Ferdinando
Mottola, Francesco Ferdinando
La Marca, Aniello
De Pascale, Ilaria
Albano, Giovanni
Rosa, Nicola
author_sort Gioia, Marco
collection PubMed
description The purpose of this study is to evaluate choroidal thickness (ChT) at the subfoveal and peripheral level after the instillation of 0.5% tropicamide + 10% phenylephrine 9 hydrochloride eye drops by using OCT scans in enhanced depth image (EDI) mode. In total, 53 patients (30 males and 23 females) were involved, and the mean age was 25.62 ± 2.41 (age range: 23–36). The dominant eye was treated with tropicamide + phenylephrine (Visumidriatic Fenil 100 mg/mL + 5 mg/mL, Visufarma) while the nondominant eye was used as the control. An OCT analysis was performed on both eyes before and 30 min after the instillation of a drop of mydriatic in the dominant eye. The ChT was measured by using the OCT software measurement tool (Spectralis; Heidelberg Engineering; Heidelberg, Germany, version 6.0). The results showed a statistically significant ChT decrease (p = 0.009) in the temporal sector after the treatment with tropicamide + phenylephrine. In the subfoveal and nasal sectors, no statistically significant ChT changes were detected (p = 0.94; p = 0.85) following the administration of the mydriatic eye drops. The ChT thinning in the temporal sector following the instillation of the tropicamide + phenylephrine eye drops suggests that in the case of ChT studies, mydriatic administration should be avoided.
format Online
Article
Text
id pubmed-10573589
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-105735892023-10-14 Evaluation of Tropicamide–Phenylephrine Mydriatic Eye Drop Instillation on Choroidal Thickness Gioia, Marco De Bernardo, Maddalena Pagliarulo, Sergio Cione, Ferdinando Mottola, Francesco Ferdinando La Marca, Aniello De Pascale, Ilaria Albano, Giovanni Rosa, Nicola J Clin Med Article The purpose of this study is to evaluate choroidal thickness (ChT) at the subfoveal and peripheral level after the instillation of 0.5% tropicamide + 10% phenylephrine 9 hydrochloride eye drops by using OCT scans in enhanced depth image (EDI) mode. In total, 53 patients (30 males and 23 females) were involved, and the mean age was 25.62 ± 2.41 (age range: 23–36). The dominant eye was treated with tropicamide + phenylephrine (Visumidriatic Fenil 100 mg/mL + 5 mg/mL, Visufarma) while the nondominant eye was used as the control. An OCT analysis was performed on both eyes before and 30 min after the instillation of a drop of mydriatic in the dominant eye. The ChT was measured by using the OCT software measurement tool (Spectralis; Heidelberg Engineering; Heidelberg, Germany, version 6.0). The results showed a statistically significant ChT decrease (p = 0.009) in the temporal sector after the treatment with tropicamide + phenylephrine. In the subfoveal and nasal sectors, no statistically significant ChT changes were detected (p = 0.94; p = 0.85) following the administration of the mydriatic eye drops. The ChT thinning in the temporal sector following the instillation of the tropicamide + phenylephrine eye drops suggests that in the case of ChT studies, mydriatic administration should be avoided. MDPI 2023-10-04 /pmc/articles/PMC10573589/ /pubmed/37834998 http://dx.doi.org/10.3390/jcm12196355 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gioia, Marco
De Bernardo, Maddalena
Pagliarulo, Sergio
Cione, Ferdinando
Mottola, Francesco Ferdinando
La Marca, Aniello
De Pascale, Ilaria
Albano, Giovanni
Rosa, Nicola
Evaluation of Tropicamide–Phenylephrine Mydriatic Eye Drop Instillation on Choroidal Thickness
title Evaluation of Tropicamide–Phenylephrine Mydriatic Eye Drop Instillation on Choroidal Thickness
title_full Evaluation of Tropicamide–Phenylephrine Mydriatic Eye Drop Instillation on Choroidal Thickness
title_fullStr Evaluation of Tropicamide–Phenylephrine Mydriatic Eye Drop Instillation on Choroidal Thickness
title_full_unstemmed Evaluation of Tropicamide–Phenylephrine Mydriatic Eye Drop Instillation on Choroidal Thickness
title_short Evaluation of Tropicamide–Phenylephrine Mydriatic Eye Drop Instillation on Choroidal Thickness
title_sort evaluation of tropicamide–phenylephrine mydriatic eye drop instillation on choroidal thickness
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573589/
https://www.ncbi.nlm.nih.gov/pubmed/37834998
http://dx.doi.org/10.3390/jcm12196355
work_keys_str_mv AT gioiamarco evaluationoftropicamidephenylephrinemydriaticeyedropinstillationonchoroidalthickness
AT debernardomaddalena evaluationoftropicamidephenylephrinemydriaticeyedropinstillationonchoroidalthickness
AT pagliarulosergio evaluationoftropicamidephenylephrinemydriaticeyedropinstillationonchoroidalthickness
AT cioneferdinando evaluationoftropicamidephenylephrinemydriaticeyedropinstillationonchoroidalthickness
AT mottolafrancescoferdinando evaluationoftropicamidephenylephrinemydriaticeyedropinstillationonchoroidalthickness
AT lamarcaaniello evaluationoftropicamidephenylephrinemydriaticeyedropinstillationonchoroidalthickness
AT depascaleilaria evaluationoftropicamidephenylephrinemydriaticeyedropinstillationonchoroidalthickness
AT albanogiovanni evaluationoftropicamidephenylephrinemydriaticeyedropinstillationonchoroidalthickness
AT rosanicola evaluationoftropicamidephenylephrinemydriaticeyedropinstillationonchoroidalthickness