Where Are We and Where to Next?—The Future of Perianal Crohn’s Disease Management

Perianal fistulizing Crohn’s Disease (pCD) affects about 25% of patients with Crohn’s Disease (CD). It remains a difficult entity to manage with a therapeutic ceiling of treatment success despite improving medical and surgical management. The refractory nature of the disease calls for an imminent ne...

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Detalles Bibliográficos
Autores principales: Anandabaskaran, Sulak, Hanna, Luke, Iqbal, Nusrat, Constable, Laura, Tozer, Phil, Hart, Ailsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573672/
https://www.ncbi.nlm.nih.gov/pubmed/37835022
http://dx.doi.org/10.3390/jcm12196379
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author Anandabaskaran, Sulak
Hanna, Luke
Iqbal, Nusrat
Constable, Laura
Tozer, Phil
Hart, Ailsa
author_facet Anandabaskaran, Sulak
Hanna, Luke
Iqbal, Nusrat
Constable, Laura
Tozer, Phil
Hart, Ailsa
author_sort Anandabaskaran, Sulak
collection PubMed
description Perianal fistulizing Crohn’s Disease (pCD) affects about 25% of patients with Crohn’s Disease (CD). It remains a difficult entity to manage with a therapeutic ceiling of treatment success despite improving medical and surgical management. The refractory nature of the disease calls for an imminent need to better understand its immunopathogenesis and classification to better streamline our treatment options. In this article, we overview the current state of pCD management and discuss where the future of its management may lie.
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spelling pubmed-105736722023-10-14 Where Are We and Where to Next?—The Future of Perianal Crohn’s Disease Management Anandabaskaran, Sulak Hanna, Luke Iqbal, Nusrat Constable, Laura Tozer, Phil Hart, Ailsa J Clin Med Review Perianal fistulizing Crohn’s Disease (pCD) affects about 25% of patients with Crohn’s Disease (CD). It remains a difficult entity to manage with a therapeutic ceiling of treatment success despite improving medical and surgical management. The refractory nature of the disease calls for an imminent need to better understand its immunopathogenesis and classification to better streamline our treatment options. In this article, we overview the current state of pCD management and discuss where the future of its management may lie. MDPI 2023-10-06 /pmc/articles/PMC10573672/ /pubmed/37835022 http://dx.doi.org/10.3390/jcm12196379 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Anandabaskaran, Sulak
Hanna, Luke
Iqbal, Nusrat
Constable, Laura
Tozer, Phil
Hart, Ailsa
Where Are We and Where to Next?—The Future of Perianal Crohn’s Disease Management
title Where Are We and Where to Next?—The Future of Perianal Crohn’s Disease Management
title_full Where Are We and Where to Next?—The Future of Perianal Crohn’s Disease Management
title_fullStr Where Are We and Where to Next?—The Future of Perianal Crohn’s Disease Management
title_full_unstemmed Where Are We and Where to Next?—The Future of Perianal Crohn’s Disease Management
title_short Where Are We and Where to Next?—The Future of Perianal Crohn’s Disease Management
title_sort where are we and where to next?—the future of perianal crohn’s disease management
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573672/
https://www.ncbi.nlm.nih.gov/pubmed/37835022
http://dx.doi.org/10.3390/jcm12196379
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