Development of a Cytotoxic Antibody–Drug Conjugate Targeting Membrane Immunoglobulin E-Positive Cells

High numbers of membrane immunoglobulin E (IgE)-positive cells are characteristic of allergic conditions, atopic dermatitis, or IgE myeloma. Antibodies targeting the extracellular membrane-proximal domain of the membranous IgE-B-cell receptor (BCR) fragment can be used for specific depletion of IgE-...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodak, Aleksandra, Stadlbauer, Katharina, Bobbili, Madhusudhan Reddy, Smrzka, Oskar, Rüker, Florian, Wozniak Knopp, Gordana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573690/
https://www.ncbi.nlm.nih.gov/pubmed/37834445
http://dx.doi.org/10.3390/ijms241914997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573690/
https://www.ncbi.nlm.nih.gov/pubmed/37834445
http://dx.doi.org/10.3390/ijms241914997

Ejemplares similares