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Development of a Cytotoxic Antibody–Drug Conjugate Targeting Membrane Immunoglobulin E-Positive Cells

High numbers of membrane immunoglobulin E (IgE)-positive cells are characteristic of allergic conditions, atopic dermatitis, or IgE myeloma. Antibodies targeting the extracellular membrane-proximal domain of the membranous IgE-B-cell receptor (BCR) fragment can be used for specific depletion of IgE-...

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Detalles Bibliográficos
Autores principales:	Rodak, Aleksandra, Stadlbauer, Katharina, Bobbili, Madhusudhan Reddy, Smrzka, Oskar, Rüker, Florian, Wozniak Knopp, Gordana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573690/ https://www.ncbi.nlm.nih.gov/pubmed/37834445 http://dx.doi.org/10.3390/ijms241914997

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