Hepatic SPARC Expression Is Associated with Inflammasome Activation during the Progression of Non-Alcoholic Fatty Liver Disease in Both Mice and Morbidly Obese Patients

The severity of non-alcoholic fatty liver disease (NAFLD) ranges from simple steatosis to steatohepatitis, and it is not yet clearly understood which patients will progress to liver fibrosis or cirrhosis. SPARC (Secreted Protein Acidic and Rich in Cysteine) has been involved in NAFLD pathogenesis in...

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Detalles Bibliográficos
Autores principales: Onorato, Agostina M., Lameroli Mauriz, Lucía, Bayo, Juan, Fiore, Esteban, Cantero, María José, Bueloni, Barbara, García, Mariana, Lagües, Cecilia, Martínez-Duartez, Pedro, Menaldi, Gabriel, Paleari, Nicolas, Atorrasagasti, Catalina, Mazzolini, Guillermo D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573696/
https://www.ncbi.nlm.nih.gov/pubmed/37834291
http://dx.doi.org/10.3390/ijms241914843

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