T-SPOT.TB Reactivity in Southern African Children With and Without in Utero Human Immunodeficiency Virus Exposure

Infants who are human immunodeficiency virus (HIV)-exposed uninfected (iHEU) experience higher risk of infectious morbidity than infants HIV-unexposed uninfected (iHUU). We compared tuberculosis (TB) infection prevalence in 418 Bacillus Calmette-Guérin vaccinated sub-Saharan African iHEU and iHUU ag...

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Autores principales: Iwase, Saori C, Edlefsen, Paul T, Bhebhe, Lynnette, Motsumi, Kesego, Moyo, Sikhulile, Happel, Anna-Ursula, Shao, Danica, Mmasa, Nicholas, Schenkel, Sara, Gasper, Melanie A, Dubois, Melanie, Files, Megan A, Seshadri, Chetan, Duffy, Fergal, Aitchison, John, Netea, Mihai G, Jao, Jennifer, Cameron, Donald W, Gray, Clive M, Jaspan, Heather B, Powis, Kathleen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573724/
https://www.ncbi.nlm.nih.gov/pubmed/37293702
http://dx.doi.org/10.1093/cid/ciad356
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author Iwase, Saori C
Edlefsen, Paul T
Bhebhe, Lynnette
Motsumi, Kesego
Moyo, Sikhulile
Happel, Anna-Ursula
Shao, Danica
Mmasa, Nicholas
Schenkel, Sara
Gasper, Melanie A
Dubois, Melanie
Files, Megan A
Seshadri, Chetan
Duffy, Fergal
Aitchison, John
Netea, Mihai G
Jao, Jennifer
Cameron, Donald W
Gray, Clive M
Jaspan, Heather B
Powis, Kathleen M
author_facet Iwase, Saori C
Edlefsen, Paul T
Bhebhe, Lynnette
Motsumi, Kesego
Moyo, Sikhulile
Happel, Anna-Ursula
Shao, Danica
Mmasa, Nicholas
Schenkel, Sara
Gasper, Melanie A
Dubois, Melanie
Files, Megan A
Seshadri, Chetan
Duffy, Fergal
Aitchison, John
Netea, Mihai G
Jao, Jennifer
Cameron, Donald W
Gray, Clive M
Jaspan, Heather B
Powis, Kathleen M
author_sort Iwase, Saori C
collection PubMed
description Infants who are human immunodeficiency virus (HIV)-exposed uninfected (iHEU) experience higher risk of infectious morbidity than infants HIV-unexposed uninfected (iHUU). We compared tuberculosis (TB) infection prevalence in 418 Bacillus Calmette-Guérin vaccinated sub-Saharan African iHEU and iHUU aged 9–18 months using T-SPOT.TB. Prevalence of TB infection was low and did not differ by HIV exposure status.
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spelling pubmed-105737242023-10-14 T-SPOT.TB Reactivity in Southern African Children With and Without in Utero Human Immunodeficiency Virus Exposure Iwase, Saori C Edlefsen, Paul T Bhebhe, Lynnette Motsumi, Kesego Moyo, Sikhulile Happel, Anna-Ursula Shao, Danica Mmasa, Nicholas Schenkel, Sara Gasper, Melanie A Dubois, Melanie Files, Megan A Seshadri, Chetan Duffy, Fergal Aitchison, John Netea, Mihai G Jao, Jennifer Cameron, Donald W Gray, Clive M Jaspan, Heather B Powis, Kathleen M Clin Infect Dis Brief Report Infants who are human immunodeficiency virus (HIV)-exposed uninfected (iHEU) experience higher risk of infectious morbidity than infants HIV-unexposed uninfected (iHUU). We compared tuberculosis (TB) infection prevalence in 418 Bacillus Calmette-Guérin vaccinated sub-Saharan African iHEU and iHUU aged 9–18 months using T-SPOT.TB. Prevalence of TB infection was low and did not differ by HIV exposure status. Oxford University Press 2023-06-09 /pmc/articles/PMC10573724/ /pubmed/37293702 http://dx.doi.org/10.1093/cid/ciad356 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Report
Iwase, Saori C
Edlefsen, Paul T
Bhebhe, Lynnette
Motsumi, Kesego
Moyo, Sikhulile
Happel, Anna-Ursula
Shao, Danica
Mmasa, Nicholas
Schenkel, Sara
Gasper, Melanie A
Dubois, Melanie
Files, Megan A
Seshadri, Chetan
Duffy, Fergal
Aitchison, John
Netea, Mihai G
Jao, Jennifer
Cameron, Donald W
Gray, Clive M
Jaspan, Heather B
Powis, Kathleen M
T-SPOT.TB Reactivity in Southern African Children With and Without in Utero Human Immunodeficiency Virus Exposure
title T-SPOT.TB Reactivity in Southern African Children With and Without in Utero Human Immunodeficiency Virus Exposure
title_full T-SPOT.TB Reactivity in Southern African Children With and Without in Utero Human Immunodeficiency Virus Exposure
title_fullStr T-SPOT.TB Reactivity in Southern African Children With and Without in Utero Human Immunodeficiency Virus Exposure
title_full_unstemmed T-SPOT.TB Reactivity in Southern African Children With and Without in Utero Human Immunodeficiency Virus Exposure
title_short T-SPOT.TB Reactivity in Southern African Children With and Without in Utero Human Immunodeficiency Virus Exposure
title_sort t-spot.tb reactivity in southern african children with and without in utero human immunodeficiency virus exposure
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573724/
https://www.ncbi.nlm.nih.gov/pubmed/37293702
http://dx.doi.org/10.1093/cid/ciad356
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