Cargando…

Molecular Dynamics Mappings of the CCT/TRiC Complex-Mediated Protein Folding Cycle Using Diffracted X-ray Tracking

The CCT/TRiC complex is a type II chaperonin that undergoes ATP-driven conformational changes during its functional cycle. Structural studies have provided valuable insights into the mechanism of this process, but real-time dynamics analyses of mammalian type II chaperonins are still scarce. We used...

Descripción completa

Detalles Bibliográficos
Autores principales:	Araki, Kazutaka, Watanabe-Nakayama, Takahiro, Sasaki, Daisuke, Sasaki, Yuji C., Mio, Kazuhiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573753/ https://www.ncbi.nlm.nih.gov/pubmed/37834298 http://dx.doi.org/10.3390/ijms241914850

Ejemplares similares

Functional Subunits of Eukaryotic Chaperonin CCT/TRiC in Protein Folding
por: Kabir, M. Anaul, et al.
Publicado: (2011)

Modulation of STAT3 Folding and Function by TRiC/CCT Chaperonin
por: Kasembeli, Moses, et al.
Publicado: (2014)

Asymmetry in the function and dynamics of the cytosolic group II chaperonin CCT/TRiC
por: Yamamoto, Yohei Y., et al.
Publicado: (2017)

Structural basis of plp2-mediated cytoskeletal protein folding by TRiC/CCT
por: Han, Wenyu, et al.
Publicado: (2023)

TRiC/CCT chaperonin is required for the folding and inhibitory effect of WDTC1 on adipogenesis
por: Tang, Wen-Shuai, et al.
Publicado: (2023)

Mechanism of lid closure in the eukaryotic chaperonin TRiC/CCT
por: Booth, Christopher R, et al.
Publicado: (2008)

The Cytosolic Chaperonin CCT/TRiC and Cancer Cell Proliferation
por: Boudiaf-Benmammar, Chafika, et al.
Publicado: (2013)

Contribution of the Type II Chaperonin, TRiC/CCT, to Oncogenesis
por: Roh, Soung-Hun, et al.
Publicado: (2015)

Regulation of GPCR expression through an interaction with CCT7, a subunit of the CCT/TRiC complex
por: Génier, Samuel, et al.
Publicado: (2016)

Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM
por: Liu, Caixuan, et al.
Publicado: (2023)

Chaperonin TRiC/CCT supports mitotic exit and entry into endocycle in Drosophila
por: Ohhara, Yuya, et al.
Publicado: (2019)

Disruption of actin dynamics induces autophagy of the eukaryotic chaperonin TRiC/CCT
por: Date, Yuki, et al.
Publicado: (2022)

Structure of the human TRiC/CCT Subunit 5 associated with hereditary sensory neuropathy
por: Pereira, Jose H., et al.
Publicado: (2017)

TRiC/CCT chaperonins are essential for organ growth by interacting with insulin/TOR signaling in Drosophila
por: Kim, Ah-Ram, et al.
Publicado: (2019)

Regeneration in starved planarians depends on TRiC/CCT subunits modulating the unfolded protein response
por: Gutiérrez‐Gutiérrez, Óscar, et al.
Publicado: (2021)

Snapshots of actin and tubulin folding inside the TRiC chaperonin
por: Kelly, John J., et al.
Publicado: (2022)

The Molecular Chaperone CCT/TRiC: An Essential Component of Proteostasis and a Potential Modulator of Protein Aggregation
por: Grantham, Julie
Publicado: (2020)

Chaperonin containing TCP-1 (CCT/TRiC) is a novel therapeutic and diagnostic target for neuroblastoma
por: Cox, Amanda, et al.
Publicado: (2022)

Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly-made proteins with complex topologies
por: Yam, Alice Y., et al.
Publicado: (2008)

Recognition of the CCT5 di‐Glu degron by CRL4(DCAF12) is dependent on TRiC assembly
por: Pla‐Prats, Carlos, et al.
Publicado: (2023)

The Role of TRiC-enhanced Actin Folding in Leber Congenital Amaurosis
por: Berger, Silke, et al.
Publicado: (2023)

Diffracted X-ray Tracking Method for Measuring Intramolecular Dynamics of Membrane Proteins
por: Fujimura, Shoko, et al.
Publicado: (2022)

Caenorhabditis elegans chaperonin CCT/TRiC is required for actin and tubulin biogenesis and microvillus formation in intestinal epithelial cells
por: Saegusa, Keiko, et al.
Publicado: (2014)

State-dependent sequential allostery exhibited by chaperonin TRiC/CCT revealed by network analysis of Cryo-EM maps
por: Zhang, Yan, et al.
Publicado: (2020)

The TRiC Chaperonin Controls Reovirus Replication through Outer-Capsid Folding
por: Knowlton, Jonathan J., et al.
Publicado: (2018)

Real-Time Observation of Capsaicin-Induced Intracellular Domain Dynamics of TRPV1 Using the Diffracted X-ray Tracking Method
por: Mio, Kazuhiro, et al.
Publicado: (2023)

The TRiC/CCT Chaperone Is Implicated in Alzheimer's Disease Based on Patient GWAS and an RNAi Screen in Aβ-Expressing Caenorhabditis elegans
por: Khabirova, Eleonora, et al.
Publicado: (2014)

TRiC/CCT Complex, a Binding Partner of NS1 Protein, Supports the Replication of Zika Virus in Both Mammalians and Mosquitoes
por: Wang, Yuchen, et al.
Publicado: (2020)

Native mass spectrometry analyses of chaperonin complex TRiC/CCT reveal subunit N-terminal processing and re-association patterns
por: Collier, Miranda P., et al.
Publicado: (2021)

Diffracted X-ray Blinking Tracks Single Protein Motions
por: Sekiguchi, Hiroshi, et al.
Publicado: (2018)

TRiC’s tricks inhibit huntingtin aggregation
por: Shahmoradian, Sarah H, et al.
Publicado: (2013)

Living-Cell Diffracted X-ray Tracking Analysis Confirmed Internal Salt Bridge Is Critical for Ligand-Induced Twisting Motion of Serotonin Receptors
por: Mio, Kazuhiro, et al.
Publicado: (2021)

Laboratory diffracted x-ray blinking to monitor picometer motions of protein molecules and application to crystalline materials
por: Arai, Tatsuya, et al.
Publicado: (2021)

Development of a yeast internal-subunit eGFP labeling strategy and its application in subunit identification in eukaryotic group II chaperonin TRiC/CCT
por: Zang, Yunxiang, et al.
Publicado: (2018)

Involvement of T-complex protein 1-ring complex/chaperonin containing T-complex protein 1 (TRiC/CCT) in retrograde axonal transport through tau phosphorylation
por: Chen, Xu-Qiao
Publicado: (2019)

Dynamic motions of ice-binding proteins in living Caenorhabditis elegans using diffracted X-ray blinking and tracking
por: Kuramochi, Masahiro, et al.
Publicado: (2022)

Diffracted X-ray Tracking for Observing the Internal Motions of Individual Protein Molecules and Its Extended Methodologies
por: Sasaki, Yuji C.
Publicado: (2023)

Differential conformational modulations of MreB folding upon interactions with GroEL/ES and TRiC chaperonin components
por: Moparthi, Satish Babu, et al.
Publicado: (2016)

A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle
por: Park, Junsun, et al.
Publicado: (2023)

Comparison of the Molecular Motility of Tubulin Dimeric Isoforms: Molecular Dynamics Simulations and Diffracted X-ray Tracking Study
por: Yamane, Tsutomu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_tpmjuq8u0j698795ugh7eo2g7o