Pharmacokinetic Model-Based Control across the Blood–Brain Barrier for Circadian Entrainment

The ability to shift circadian phase in vivo has the potential to offer substantial health benefits. However, the blood–brain barrier prevents the absorption of the majority of large and many small molecules, posing a challenge to neurological pharmaceutical development. Motivated by the presence of...

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Detalles Bibliográficos
Autores principales: Murdoch, Síofra Ó., Aiello, Eleonora M., Doyle, Francis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573769/
https://www.ncbi.nlm.nih.gov/pubmed/37834278
http://dx.doi.org/10.3390/ijms241914830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573769/
https://www.ncbi.nlm.nih.gov/pubmed/37834278
http://dx.doi.org/10.3390/ijms241914830

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