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Evaluation of Clinical Outcomes after Poor-Quality Embryo Transfer and Prognostic Parameters
We aimed to investigate the clinical results following poor-quality embryo transfer and the parameters to foresee the prognosis. In this study, 2123 cycles that had day 3 and day 5 single-fresh embryo with poor-quality embryo transfers and good-quality embryo transfers were compared. The cycles acco...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573848/ https://www.ncbi.nlm.nih.gov/pubmed/37834880 http://dx.doi.org/10.3390/jcm12196236 |
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author | Kadioglu, Nezaket Kahyaoğlu, İnci Kaplanoğlu, İskender Dilbaz, Serdar Engin Üstün, Yaprak |
author_facet | Kadioglu, Nezaket Kahyaoğlu, İnci Kaplanoğlu, İskender Dilbaz, Serdar Engin Üstün, Yaprak |
author_sort | Kadioglu, Nezaket |
collection | PubMed |
description | We aimed to investigate the clinical results following poor-quality embryo transfer and the parameters to foresee the prognosis. In this study, 2123 cycles that had day 3 and day 5 single-fresh embryo with poor-quality embryo transfers and good-quality embryo transfers were compared. The cycles according to transfer day were evaluated by conducting a subgroup analysis. The correlation between all the obtained demographic characteristics, controlled ovarian stimulation parameters, and cycle results were analysed. Clinical pregnancy was established in 53 patients that underwent transfer in the poor-quality embryo group (14.9%). Of these patients, 36 had live birth (live birth rate per clinical pregnancy 67.9%). In cleavage-stage embryos, live birth rates per clinical pregnancy were higher in poor-quality blastocyst transfer. When analysing the factors affecting live births in the poor-quality embryo group, as the total gonadotropin dose increases, the probability of live birth decreases, as in the probability of hCG positivity. In conclusion, although the probability of pregnancy is low, when clinical pregnancy is established, there is a high chance of having a live birth after poor-quality embryo transfers. This could be regarded as an acceptable option in cycles when only poor-quality embryos are available. |
format | Online Article Text |
id | pubmed-10573848 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-105738482023-10-14 Evaluation of Clinical Outcomes after Poor-Quality Embryo Transfer and Prognostic Parameters Kadioglu, Nezaket Kahyaoğlu, İnci Kaplanoğlu, İskender Dilbaz, Serdar Engin Üstün, Yaprak J Clin Med Article We aimed to investigate the clinical results following poor-quality embryo transfer and the parameters to foresee the prognosis. In this study, 2123 cycles that had day 3 and day 5 single-fresh embryo with poor-quality embryo transfers and good-quality embryo transfers were compared. The cycles according to transfer day were evaluated by conducting a subgroup analysis. The correlation between all the obtained demographic characteristics, controlled ovarian stimulation parameters, and cycle results were analysed. Clinical pregnancy was established in 53 patients that underwent transfer in the poor-quality embryo group (14.9%). Of these patients, 36 had live birth (live birth rate per clinical pregnancy 67.9%). In cleavage-stage embryos, live birth rates per clinical pregnancy were higher in poor-quality blastocyst transfer. When analysing the factors affecting live births in the poor-quality embryo group, as the total gonadotropin dose increases, the probability of live birth decreases, as in the probability of hCG positivity. In conclusion, although the probability of pregnancy is low, when clinical pregnancy is established, there is a high chance of having a live birth after poor-quality embryo transfers. This could be regarded as an acceptable option in cycles when only poor-quality embryos are available. MDPI 2023-09-27 /pmc/articles/PMC10573848/ /pubmed/37834880 http://dx.doi.org/10.3390/jcm12196236 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Kadioglu, Nezaket Kahyaoğlu, İnci Kaplanoğlu, İskender Dilbaz, Serdar Engin Üstün, Yaprak Evaluation of Clinical Outcomes after Poor-Quality Embryo Transfer and Prognostic Parameters |
title | Evaluation of Clinical Outcomes after Poor-Quality Embryo Transfer and Prognostic Parameters |
title_full | Evaluation of Clinical Outcomes after Poor-Quality Embryo Transfer and Prognostic Parameters |
title_fullStr | Evaluation of Clinical Outcomes after Poor-Quality Embryo Transfer and Prognostic Parameters |
title_full_unstemmed | Evaluation of Clinical Outcomes after Poor-Quality Embryo Transfer and Prognostic Parameters |
title_short | Evaluation of Clinical Outcomes after Poor-Quality Embryo Transfer and Prognostic Parameters |
title_sort | evaluation of clinical outcomes after poor-quality embryo transfer and prognostic parameters |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573848/ https://www.ncbi.nlm.nih.gov/pubmed/37834880 http://dx.doi.org/10.3390/jcm12196236 |
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