Cargando…

Substance P and Neurokinin-1 Receptor System in Thyroid Cancer: Potential Targets for New Molecular Therapies

In recent years, numerous approaches have been developed to comprehend the molecular alterations underlying thyroid cancer (TC) oncogenesis and explore novel therapeutic strategies for TC. It is now well established that the neurokinin-1 receptor (NK-1R) is overexpressed in cancer cells and that NK-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Isorna, Inmaculada, González-Moles, Miguel Ángel, Muñoz, Miguel, Esteban, Francisco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573850/ https://www.ncbi.nlm.nih.gov/pubmed/37835053 http://dx.doi.org/10.3390/jcm12196409

Ejemplares similares

The substance P and neurokinin-1 receptor system in human thyroid cancer: An immunohistochemical study
por: Isorna, Inmaculada, et al.
Publicado: (2020)

Substance P and Neurokinin 1 Receptor in Chronic Inflammation and Cancer of the Head and Neck: A Review of the Literature
por: Esteban, Francisco, et al.
Publicado: (2021)

Involvement of the Substance P/Neurokinin-1 Receptor System in Cancer
por: Coveñas, Rafael, et al.
Publicado: (2022)

Neurokinin-2 receptor negatively modulates substance P responses by forming complex with Neurokinin-1 receptor
por: Nguyen, Lan Phuong, et al.
Publicado: (2023)

Prognostic Significance of Substance P/Neurokinin 1 Receptor and Its Association with Hormonal Receptors in Breast Carcinoma
por: Mehboob, Riffat, et al.
Publicado: (2021)

Significance of the Overexpression of Substance P and Its Receptor NK-1R in Head and Neck Carcinogenesis: A Systematic Review and Meta-Analysis
por: González-Moles, Miguel Ángel, et al.
Publicado: (2021)

Activation of neurokinin-1 receptors up-regulates substance P and neurokinin-1 receptor expression in murine pancreatic acinar cells
por: Koh, Yung-Hua, et al.
Publicado: (2012)

Neurokinin-1 Receptor Antagonists against Hepatoblastoma
por: Muñoz, Miguel, et al.
Publicado: (2019)

The Role of Neurokinin-1 Receptor in the Microenvironment of Inflammation and Cancer
por: Rosso, Marisa, et al.
Publicado: (2012)

Functional neurokinin 1 receptors for substance P are expressed by human vascular endothelium
Publicado: (1993)

Selective G protein signaling driven by Substance P-Neurokinin Receptor dynamics
por: Harris, Julian A., et al.
Publicado: (2021)

The Neurokinin-1 Receptor Antagonist Aprepitant: An Intelligent Bullet against Cancer?
por: Muñoz, Miguel, et al.
Publicado: (2020)

Neurokinin-1 Receptor Antagonists as a Potential Novel Therapeutic Option for Osteosarcoma Patients
por: Robinson, Prema, et al.
Publicado: (2023)

Alcohol dependence potentiates substance P/neurokinin-1 receptor signaling in the rat central nucleus of amygdala
por: Khom, S., et al.
Publicado: (2020)

Substance P and Neurokinin 1 receptor - expression is affected in the ileum of mice with mutation in the W locus
por: Faussone-Pellegrini, Maria-Simonetta, et al.
Publicado: (2006)

Human microglia and astrocytes constitutively express the neurokinin-1 receptor and functionally respond to substance P
por: Burmeister, Amanda R., et al.
Publicado: (2017)

Substance P/ Neurokinin-1 Receptor, Trigeminal Ganglion, Latency, and Coronavirus Infection-Is There Any Link?
por: Mehboob, Riffat, et al.
Publicado: (2021)

The Repurposing of Non-Peptide Neurokinin-1 Receptor Antagonists as Antitumor Drugs: An Urgent Challenge for Aprepitant
por: Coveñas, Rafael, et al.
Publicado: (2023)

The Neurokinin-1 Receptor Is Essential for the Viability of Human Glioma Cells: A Possible Target for Treating Glioblastoma
por: Muñoz, Mario F., et al.
Publicado: (2022)

Neurokinin-1 Receptor Antagonists as Antitumor Drugs in Gastrointestinal Cancer: A New Approach
por: Muñoz, Miguel, et al.
Publicado: (2016)

Functional Neurokinin and NMDA Receptor Activity in an Animal Naturally Lacking Substance P: The Naked Mole-Rat
por: Brand, Antje, et al.
Publicado: (2010)

Structural insights into the activation of neurokinin 2 receptor by neurokinin A
por: Sun, Wenjing, et al.
Publicado: (2022)

Activation of the neurokinin-1 receptor by substance P triggers the release of substance P from cultured adult rat dorsal root ganglion neurons
por: Tang, He-Bin, et al.
Publicado: (2007)

The role of neurokinin-1 (substance P) antagonists in the prevention of postoperative nausea and vomiting
por: Okafor, Dionne, et al.
Publicado: (2017)

Effects of Substance P and Neurokinin A on the Contractile Activity of Inflamed Porcine Uterus
por: Brzozowska, Marta, et al.
Publicado: (2022)

High expression of substance P and its receptor neurokinin-1 receptor in colorectal cancer is associated with tumor progression and prognosis
por: Chen, Xiao-Yi, et al.
Publicado: (2016)

The Neurokinin-1 Receptor Antagonist Aprepitant, a New Drug for the Treatment of Hematological Malignancies: Focus on Acute Myeloid Leukemia
por: Muñoz, Miguel, et al.
Publicado: (2020)

Substance P Immunoreactivity Exhibits Frequent Colocalization with Kisspeptin and Neurokinin B in the Human Infundibular Region
por: Hrabovszky, Erik, et al.
Publicado: (2013)

Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors
por: Wtorek, Karol, et al.
Publicado: (2019)

The Neurokinin-1 Receptor Is a Target in Pediatric Rhabdoid Tumors
por: Kolorz, Julian, et al.
Publicado: (2021)

Neurokinin-1 Receptor as a potential drug target for COVID-19 treatment
por: Mehboob, Riffat
Publicado: (2021)

Role of protein kinase C in caerulein induced expression of substance P and neurokinin-1-receptors in murine pancreatic acinar cells
por: Koh, Yung-Hua, et al.
Publicado: (2011)

Analgesia by deletion of spinal neurokinin 1 receptor expressing neurons using a bioengineered substance P-Pseudomonas exotoxin conjugate
por: Iadarola, Michael J, et al.
Publicado: (2017)

Neurokinin-1 Receptor Inhibition and Cough
por: Turner, Richard D., et al.
Publicado: (2021)

Neurokinin 1 Receptor Antagonists for Pruritus
por: Alam, Majid, et al.
Publicado: (2021)

Neurokinin-1 Receptor Antagonist Treatment in Polymicrobial Sepsis: Molecular Insights
por: Hegde, Akhil, et al.
Publicado: (2010)

Application of Neurokinin-1 Receptor in Targeted Strategies for Glioma Treatment. Part I: Synthesis and Evaluation of Substance P Fragments Labeled with (99m)Tc and (177)Lu as Potential Receptor Radiopharmaceuticals
por: Majkowska-Pilip, Agnieszka, et al.
Publicado: (2018)

Substance P/Neurokinin 1 and Trigeminal System: A Possible Link to the Pathogenesis in Sudden Perinatal Deaths
por: Mehboob, Riffat
Publicado: (2017)

Mycoplasma hyopneumoniae surface-associated proteases cleave bradykinin, substance P, neurokinin A and neuropeptide Y
por: Jarocki, Veronica Maria, et al.
Publicado: (2019)

Mapping of neurokinin-like immunoreactivity in the human brainstem
por: Coveñas, Rafael, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_c36f2734l9990eetobgfk272fb