Cargando…

Insulin Receptor Isoforms and Insulin Growth Factor-like Receptors: Implications in Cell Signaling, Carcinogenesis, and Chemoresistance

This comprehensive review thoroughly explores the intricate involvement of insulin receptor (IR) isoforms and insulin-like growth factor receptors (IGFRs) in the context of the insulin and insulin-like growth factor (IGF) signaling (IIS) pathway. This elaborate system encompasses ligands, receptors,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Galal, Mariam Ahmed, Alouch, Samhar Samer, Alsultan, Buthainah Saad, Dahman, Huda, Alyabis, Nouf Abdullah, Alammar, Sarah Ammar, Aljada, Ahmad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573852/ https://www.ncbi.nlm.nih.gov/pubmed/37834454 http://dx.doi.org/10.3390/ijms241915006

Ejemplares similares

Insulin Receptor Isoforms in Cancer
por: Vella, Veronica, et al.
Publicado: (2018)

Engineering of Insulin Receptor Isoform-Selective Insulin Analogues
por: Glendorf, Tine, et al.
Publicado: (2011)

Structural Perspectives of Insulin Receptor Isoform-Selective Insulin Analogs
por: Jiráček, Jiří, et al.
Publicado: (2017)

Altered Expression of Insulin Receptor Isoforms in Breast Cancer
por: Huang, Jiaqi, et al.
Publicado: (2011)

Insulin Receptor Isoform Variations in Prostate Cancer Cells
por: Perks, Claire M., et al.
Publicado: (2016)

Insulin Receptor Isoforms A and B as well as Insulin Receptor Substrates-1 and -2 Are Differentially Expressed in Prostate Cancer
por: Heni, Martin, et al.
Publicado: (2012)

IGF1 and IGF2 specificities to the two insulin receptor isoforms are determined by insulin receptor amino acid 718
por: Andersen, Mie, et al.
Publicado: (2017)

The Role of Insulin Receptor Isoforms in Diabetes and Its Metabolic and Vascular Complications
por: Escribano, O., et al.
Publicado: (2017)

Potential role of insulin receptor isoforms and IGF receptors in plaque instability of human and experimental atherosclerosis
por: Beneit, Nuria, et al.
Publicado: (2018)

Isoform-specific insulin receptor signaling involves different plasma membrane domains
por: Uhles, Sabine, et al.
Publicado: (2003)

Overexpression of the Insulin Receptor Isoform A Promotes Endometrial Carcinoma Cell Growth
por: Wang, Chun-Fang, et al.
Publicado: (2013)

Insulin Receptor Isoform A Modulates Metabolic Reprogramming of Breast Cancer Cells in Response to IGF2 and Insulin Stimulation
por: Vella, Veronica, et al.
Publicado: (2019)

Synchronization in G(0)/G(1) enhances the mitogenic response of cells overexpressing the human insulin receptor A isoform to insulin
por: Bonnesen, Christine, et al.
Publicado: (2009)

Insulin receptor isoform A ameliorates long-term glucose intolerance in diabetic mice
por: Diaz-Castroverde, Sabela, et al.
Publicado: (2016)

The Emerging Role of Insulin Receptor Isoforms in Thyroid Cancer: Clinical Implications and New Perspectives
por: Vella, Veronica, et al.
Publicado: (2018)

The IGF-II–Insulin Receptor Isoform-A Autocrine Signal in Cancer: Actionable Perspectives
por: Scalia, Pierluigi, et al.
Publicado: (2020)

Retraction: Overexpression of the Insulin Receptor Isoform A Promotes Endometrial Carcinoma Cell Growth
Publicado: (2021)

Insulin/Insulin-Like Growth Factor-1 Pathway in Barrett's Carcinogenesis
por: Greer, K B, et al.
Publicado: (2013)

Insulin receptor trafficking steers insulin action
por: Hausmann, Simone, et al.
Publicado: (2016)

Insulin and Insulin Receptors in Adipose Tissue Development
por: Cignarelli, Angelo, et al.
Publicado: (2019)

Insulin receptor endocytosis in the pathophysiology of insulin resistance
por: Hall, Catherine, et al.
Publicado: (2020)

Activation of the insulin receptor by an insulin mimetic peptide
por: Park, Junhee, et al.
Publicado: (2022)

Glucose-dependent effect of insulin receptor isoforms on tamoxifen antitumor activity in estrogen receptor-positive breast cancer cells
por: Stella, Stefania, et al.
Publicado: (2023)

SUN-131 The Roles of Two Insulin Receptor Isoforms in Triple Negative Breast Cancer Growth
por: Kang, Chifei, et al.
Publicado: (2020)

Insulin Receptor Isoforms Differently Regulate Cell Proliferation and Apoptosis in the Ligand-Occupied and Unoccupied State
por: Massimino, Michele, et al.
Publicado: (2021)

Tissue‐specific expression of insulin receptor isoforms in obesity/type 2 diabetes mouse models
por: Moruzzi, Noah, et al.
Publicado: (2021)

Estradiol Binds to Insulin and Insulin Receptor Decreasing Insulin Binding in vitro
por: Root-Bernstein, Robert, et al.
Publicado: (2014)

Far-western Blotting Detection of the Binding of Insulin Receptor Substrate to the Insulin Receptor
por: Peng, Jinghua, et al.
Publicado: (2023)

Insulin Restores Gestational Diabetes Mellitus–Reduced Adenosine Transport Involving Differential Expression of Insulin Receptor Isoforms in Human Umbilical Vein Endothelium
por: Westermeier, Francisco, et al.
Publicado: (2011)

β-Cell Hyperplasia Induced by Hepatic Insulin Resistance: Role of a Liver-Pancreas Endocrine Axis Through Insulin Receptor A Isoform
por: Escribano, Oscar, et al.
Publicado: (2009)

Differential interaction of Apolipoprotein-E isoforms with insulin receptors modulates brain insulin signaling in mutant human amyloid precursor protein transgenic mice
por: Chan, Elizabeth S, et al.
Publicado: (2015)

Insulin Receptor Trafficking: Consequences for Insulin Sensitivity and Diabetes
por: Chen, Yang, et al.
Publicado: (2019)

Novel Mechanisms of Tumor Promotion by the Insulin Receptor Isoform A in Triple-Negative Breast Cancer Cells
por: Vella, Veronica, et al.
Publicado: (2021)

Deciphering Brain Insulin Receptor and Insulin‐Like Growth Factor 1 Receptor Signalling
por: Kleinridders, A.
Publicado: (2016)

Modulation of insulin/IGFs pathways by sirtuin-7 inhibition in drug-induced chemoreistance
por: Aljada, Ahmad, et al.
Publicado: (2014)

PHLPP isoforms differentially regulate Akt isoforms and AS160 affecting neuronal insulin signaling and insulin resistance via Scribble
por: Sharma, Medha, et al.
Publicado: (2022)

Insulin receptors in human cancer.
por: Benson, E. A., et al.
Publicado: (1981)

Biosynthesis and regulation of the insulin receptor.
por: Gorden, P., et al.
Publicado: (1989)

Inputs and outputs of insulin receptor
por: Du, Yipeng, et al.
Publicado: (2014)

Agonism and Antagonism at the Insulin Receptor
por: Knudsen, Louise, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_a74nvnvba72022an4ljo0h6en2