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Hepatic-Specific FGF21 Knockout Abrogates Ovariectomy-Induced Obesity by Reversing Corticosterone Production

Increased glucocorticoid (GC) levels act as a master contributor to central obesity in estrogen-depleted females; however, what factors cause their increased GC production is unclear. Given (1) liver fibroblast growth factor 21 (FGF21) and GCs regulate each other’s production in a feed-forward loop,...

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Detalles Bibliográficos
Autores principales: Xu, Jiayu, Shao, Xinyu, Zeng, Haozhe, Wang, Chengxi, Li, Jiayi, Peng, Xiaoqin, Zhuo, Yong, Hua, Lun, Meng, Fengyan, Han, Xingfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573867/
https://www.ncbi.nlm.nih.gov/pubmed/37834368
http://dx.doi.org/10.3390/ijms241914922