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A modified Beckmann rearrangement for the facile synthesis of amidines and imidates via imidoyl fluoride intermediates
Herein, we report a modified Beckmann rearrangement using sulfone iminium fluoride (SIF) reagents to rapidly synthesize imidoyl fluoride intermediates. Subsequently, amidine and imidate products can be formed following the introduction of amine and alcohol nucleophiles, respectively. Overall, approx...
Autores principales: | Vogel, James A., Miller, Kirya F., Shin, Eunjeong, Krussman, Jenna M., Melvin, Patrick R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573916/ https://www.ncbi.nlm.nih.gov/pubmed/37842679 http://dx.doi.org/10.1039/d3ra06561h |
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