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Impact of Scoring Balloon Angioplasty on Lesion Preparation for DCB Treatment of Coronary Lesions

Objective: The aim of this study was to evaluate the efficacy of scoring balloon angioplasty for drug-coated balloon (DCB) treatment in percutaneous coronary intervention. Background: The scoring balloon angioplasty may play a pivotal role in enhancing the outcomes of DCB treatment. Methods: A total...

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Autores principales: Shin, Eun-Seok, Ann, Soe Hee, Jang, Mi Hee, Kim, Bitna, Kim, Tae-Hyun, Sohn, Chang-Bae, Choi, Byung Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573989/
https://www.ncbi.nlm.nih.gov/pubmed/37834898
http://dx.doi.org/10.3390/jcm12196254
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author Shin, Eun-Seok
Ann, Soe Hee
Jang, Mi Hee
Kim, Bitna
Kim, Tae-Hyun
Sohn, Chang-Bae
Choi, Byung Joo
author_facet Shin, Eun-Seok
Ann, Soe Hee
Jang, Mi Hee
Kim, Bitna
Kim, Tae-Hyun
Sohn, Chang-Bae
Choi, Byung Joo
author_sort Shin, Eun-Seok
collection PubMed
description Objective: The aim of this study was to evaluate the efficacy of scoring balloon angioplasty for drug-coated balloon (DCB) treatment in percutaneous coronary intervention. Background: The scoring balloon angioplasty may play a pivotal role in enhancing the outcomes of DCB treatment. Methods: A total of 259 patients (278 lesions) with coronary artery disease successfully treated with DCB were retrospectively enrolled. The mean age of the patients was 62.2 ± 11.1 years, and the majority of patients were men (68.7%). The study’s endpoint was defined as achieving an optimal angiographic result, which consisted of Thrombolysis in Myocardial Infarction (TIMI) flow grade 3, residual diameter stenosis ≤ 30%, and dissection less than type C after the procedure. Results: Angioplasty was performed for 61 lesions with a scoring balloon and 217 lesions with a non-scoring balloon. All lesions were TIMI flow grade 3 except two lesions in the non-scoring balloon group. The scoring balloon group had a higher prevalence of residual diameter stenosis ≤ 30% (68.9% vs. 39.6%, p < 0.001), while severe dissection, defined as type C or greater, was observed less frequently (9.8% vs. 31.8%, p = 0.001). Moreover, the scoring balloon group achieved a superior rate of optimal angiographic results (60.7% vs. 28.6%, p < 0.001). In multivariable analysis, scoring balloon (OR: 3.08 [95% confidence interval, 1.47–6.58], p = 0.003) and DCB balloon-to-artery ratios (OR: 5.46 [95% confidence interval, 1.43–21.93], p = 0.014) were independent factors in the increasing rate of optimal angiographic result. Conclusions: The application of a scoring balloon catheter for lesion preparation, aiming to make them suitable for DCB treatment, was associated with a decreased risk of severe dissection and a greater occurrence of optimal angiographic outcomes compared with non-scoring balloon angioplasty.
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spelling pubmed-105739892023-10-14 Impact of Scoring Balloon Angioplasty on Lesion Preparation for DCB Treatment of Coronary Lesions Shin, Eun-Seok Ann, Soe Hee Jang, Mi Hee Kim, Bitna Kim, Tae-Hyun Sohn, Chang-Bae Choi, Byung Joo J Clin Med Article Objective: The aim of this study was to evaluate the efficacy of scoring balloon angioplasty for drug-coated balloon (DCB) treatment in percutaneous coronary intervention. Background: The scoring balloon angioplasty may play a pivotal role in enhancing the outcomes of DCB treatment. Methods: A total of 259 patients (278 lesions) with coronary artery disease successfully treated with DCB were retrospectively enrolled. The mean age of the patients was 62.2 ± 11.1 years, and the majority of patients were men (68.7%). The study’s endpoint was defined as achieving an optimal angiographic result, which consisted of Thrombolysis in Myocardial Infarction (TIMI) flow grade 3, residual diameter stenosis ≤ 30%, and dissection less than type C after the procedure. Results: Angioplasty was performed for 61 lesions with a scoring balloon and 217 lesions with a non-scoring balloon. All lesions were TIMI flow grade 3 except two lesions in the non-scoring balloon group. The scoring balloon group had a higher prevalence of residual diameter stenosis ≤ 30% (68.9% vs. 39.6%, p < 0.001), while severe dissection, defined as type C or greater, was observed less frequently (9.8% vs. 31.8%, p = 0.001). Moreover, the scoring balloon group achieved a superior rate of optimal angiographic results (60.7% vs. 28.6%, p < 0.001). In multivariable analysis, scoring balloon (OR: 3.08 [95% confidence interval, 1.47–6.58], p = 0.003) and DCB balloon-to-artery ratios (OR: 5.46 [95% confidence interval, 1.43–21.93], p = 0.014) were independent factors in the increasing rate of optimal angiographic result. Conclusions: The application of a scoring balloon catheter for lesion preparation, aiming to make them suitable for DCB treatment, was associated with a decreased risk of severe dissection and a greater occurrence of optimal angiographic outcomes compared with non-scoring balloon angioplasty. MDPI 2023-09-28 /pmc/articles/PMC10573989/ /pubmed/37834898 http://dx.doi.org/10.3390/jcm12196254 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Shin, Eun-Seok
Ann, Soe Hee
Jang, Mi Hee
Kim, Bitna
Kim, Tae-Hyun
Sohn, Chang-Bae
Choi, Byung Joo
Impact of Scoring Balloon Angioplasty on Lesion Preparation for DCB Treatment of Coronary Lesions
title Impact of Scoring Balloon Angioplasty on Lesion Preparation for DCB Treatment of Coronary Lesions
title_full Impact of Scoring Balloon Angioplasty on Lesion Preparation for DCB Treatment of Coronary Lesions
title_fullStr Impact of Scoring Balloon Angioplasty on Lesion Preparation for DCB Treatment of Coronary Lesions
title_full_unstemmed Impact of Scoring Balloon Angioplasty on Lesion Preparation for DCB Treatment of Coronary Lesions
title_short Impact of Scoring Balloon Angioplasty on Lesion Preparation for DCB Treatment of Coronary Lesions
title_sort impact of scoring balloon angioplasty on lesion preparation for dcb treatment of coronary lesions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573989/
https://www.ncbi.nlm.nih.gov/pubmed/37834898
http://dx.doi.org/10.3390/jcm12196254
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