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Comparative Analysis of Chemical Profile and Biological Activity of Juniperus communis L. Berry Extracts
Researchers are looking for the most effective ways to extract the bioactive substances of Juniperus communis L. berries, which are capable of displaying the greatest range of biological activity, namely antimicrobial potential “against phytopathogens”, antioxidant activity and nematocidal activity....
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574284/ https://www.ncbi.nlm.nih.gov/pubmed/37836145 http://dx.doi.org/10.3390/plants12193401 |
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author | Belov, Timur Terenzhev, Dmitriy Bushmeleva, Kseniya Nikolaevna Davydova, Lilia Burkin, Konstantin Fitsev, Igor Gatiyatullina, Alsu Egorova, Anastasia Nikitin, Evgeniy |
author_facet | Belov, Timur Terenzhev, Dmitriy Bushmeleva, Kseniya Nikolaevna Davydova, Lilia Burkin, Konstantin Fitsev, Igor Gatiyatullina, Alsu Egorova, Anastasia Nikitin, Evgeniy |
author_sort | Belov, Timur |
collection | PubMed |
description | Researchers are looking for the most effective ways to extract the bioactive substances of Juniperus communis L. berries, which are capable of displaying the greatest range of biological activity, namely antimicrobial potential “against phytopathogens”, antioxidant activity and nematocidal activity. This study provides detailed information on the chemical activity, group composition and biological activity of the extracts of juniper berries of 1- and 2-year maturity (JB1 and JB2), which were obtained by using different solvents (pentane, chloroform, acetone, methanol and 70% ethanol) under various extraction conditions (maceration and ultrasound-assisted maceration (US)). Seventy percent ethanol and acetone extracts of juniper berries were analyzed via gas chromatography–mass spectrometry, and they contained monoterpenes, sesquiterpenes, polysaccharides, steroids, fatty acid esters and bicyclic monoterpenes. The antimicrobial activity was higher in the berries of 1-year maturity, while the acetone extract obtained via ultrasound-assisted maceration was the most bioactive in relation to the phytopathogens. Depending on the extraction method and the choice of solvent, the antioxidant activity with the use of US decreased by 1.5–1.9 times compared to the extracts obtained via maceration. An analysis of the nematocidal activity showed that the sensitivity to the action of extracts in Caenorhabditis elegans was significantly higher than in Caenorhabditis briggsae, particularly for the acetone extract obtained from the juniper berries of 1-year maturity. |
format | Online Article Text |
id | pubmed-10574284 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-105742842023-10-14 Comparative Analysis of Chemical Profile and Biological Activity of Juniperus communis L. Berry Extracts Belov, Timur Terenzhev, Dmitriy Bushmeleva, Kseniya Nikolaevna Davydova, Lilia Burkin, Konstantin Fitsev, Igor Gatiyatullina, Alsu Egorova, Anastasia Nikitin, Evgeniy Plants (Basel) Article Researchers are looking for the most effective ways to extract the bioactive substances of Juniperus communis L. berries, which are capable of displaying the greatest range of biological activity, namely antimicrobial potential “against phytopathogens”, antioxidant activity and nematocidal activity. This study provides detailed information on the chemical activity, group composition and biological activity of the extracts of juniper berries of 1- and 2-year maturity (JB1 and JB2), which were obtained by using different solvents (pentane, chloroform, acetone, methanol and 70% ethanol) under various extraction conditions (maceration and ultrasound-assisted maceration (US)). Seventy percent ethanol and acetone extracts of juniper berries were analyzed via gas chromatography–mass spectrometry, and they contained monoterpenes, sesquiterpenes, polysaccharides, steroids, fatty acid esters and bicyclic monoterpenes. The antimicrobial activity was higher in the berries of 1-year maturity, while the acetone extract obtained via ultrasound-assisted maceration was the most bioactive in relation to the phytopathogens. Depending on the extraction method and the choice of solvent, the antioxidant activity with the use of US decreased by 1.5–1.9 times compared to the extracts obtained via maceration. An analysis of the nematocidal activity showed that the sensitivity to the action of extracts in Caenorhabditis elegans was significantly higher than in Caenorhabditis briggsae, particularly for the acetone extract obtained from the juniper berries of 1-year maturity. MDPI 2023-09-27 /pmc/articles/PMC10574284/ /pubmed/37836145 http://dx.doi.org/10.3390/plants12193401 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Belov, Timur Terenzhev, Dmitriy Bushmeleva, Kseniya Nikolaevna Davydova, Lilia Burkin, Konstantin Fitsev, Igor Gatiyatullina, Alsu Egorova, Anastasia Nikitin, Evgeniy Comparative Analysis of Chemical Profile and Biological Activity of Juniperus communis L. Berry Extracts |
title | Comparative Analysis of Chemical Profile and Biological Activity of Juniperus communis L. Berry Extracts |
title_full | Comparative Analysis of Chemical Profile and Biological Activity of Juniperus communis L. Berry Extracts |
title_fullStr | Comparative Analysis of Chemical Profile and Biological Activity of Juniperus communis L. Berry Extracts |
title_full_unstemmed | Comparative Analysis of Chemical Profile and Biological Activity of Juniperus communis L. Berry Extracts |
title_short | Comparative Analysis of Chemical Profile and Biological Activity of Juniperus communis L. Berry Extracts |
title_sort | comparative analysis of chemical profile and biological activity of juniperus communis l. berry extracts |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574284/ https://www.ncbi.nlm.nih.gov/pubmed/37836145 http://dx.doi.org/10.3390/plants12193401 |
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