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Molecular Dynamics Simulation Study of the Selective Inhibition of Coagulation Factor IXa over Factor Xa

Thromboembolic disorders, arising from abnormal coagulation, pose a significant risk to human life in the modern world. The FDA has recently approved several anticoagulant drugs targeting factor Xa (FXa) to manage these disorders. However, these drugs have potential side effects, leading to bleeding...

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Detalles Bibliográficos
Autores principales: Yoon, Hyun Jung, Kundu, Sibsankar, Wu, Sangwook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574344/
https://www.ncbi.nlm.nih.gov/pubmed/37836752
http://dx.doi.org/10.3390/molecules28196909