Cargando…
Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases
Phytochemicals are abundantly occurring natural compounds extracted from plant sources. Rosmarinic acid (RA) is an abundant phytochemical of Lamiaceae species with various therapeutic implications for human health. In recent years, natural compounds have gained significant attention as adjuvant and...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574478/ https://www.ncbi.nlm.nih.gov/pubmed/37836581 http://dx.doi.org/10.3390/nu15194297 |
_version_ | 1785120704103972864 |
---|---|
author | Azhar, Md. Khabeer Anwar, Saleha Hasan, Gulam Mustafa Shamsi, Anas Islam, Asimul Parvez, Suhel Hassan, Md. Imtaiyaz |
author_facet | Azhar, Md. Khabeer Anwar, Saleha Hasan, Gulam Mustafa Shamsi, Anas Islam, Asimul Parvez, Suhel Hassan, Md. Imtaiyaz |
author_sort | Azhar, Md. Khabeer |
collection | PubMed |
description | Phytochemicals are abundantly occurring natural compounds extracted from plant sources. Rosmarinic acid (RA) is an abundant phytochemical of Lamiaceae species with various therapeutic implications for human health. In recent years, natural compounds have gained significant attention as adjuvant and complementary therapies to existing medications for various diseases. RA has gained popularity due to its anti-inflammatory and antioxidant properties and its roles in various life-threatening conditions, such as cancer, neurodegeneration, diabetes, etc. The present review aims to offer a comprehensive insight into the multifaceted therapeutic properties of RA, including its potential as an anticancer agent, neuroprotective effects, and antidiabetic potential. Based on the available evidences, RA could be considered a potential dietary component for treating various diseases, including cancer, diabetes and neurodegenerative disorders. |
format | Online Article Text |
id | pubmed-10574478 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-105744782023-10-14 Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases Azhar, Md. Khabeer Anwar, Saleha Hasan, Gulam Mustafa Shamsi, Anas Islam, Asimul Parvez, Suhel Hassan, Md. Imtaiyaz Nutrients Review Phytochemicals are abundantly occurring natural compounds extracted from plant sources. Rosmarinic acid (RA) is an abundant phytochemical of Lamiaceae species with various therapeutic implications for human health. In recent years, natural compounds have gained significant attention as adjuvant and complementary therapies to existing medications for various diseases. RA has gained popularity due to its anti-inflammatory and antioxidant properties and its roles in various life-threatening conditions, such as cancer, neurodegeneration, diabetes, etc. The present review aims to offer a comprehensive insight into the multifaceted therapeutic properties of RA, including its potential as an anticancer agent, neuroprotective effects, and antidiabetic potential. Based on the available evidences, RA could be considered a potential dietary component for treating various diseases, including cancer, diabetes and neurodegenerative disorders. MDPI 2023-10-09 /pmc/articles/PMC10574478/ /pubmed/37836581 http://dx.doi.org/10.3390/nu15194297 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Azhar, Md. Khabeer Anwar, Saleha Hasan, Gulam Mustafa Shamsi, Anas Islam, Asimul Parvez, Suhel Hassan, Md. Imtaiyaz Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases |
title | Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases |
title_full | Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases |
title_fullStr | Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases |
title_full_unstemmed | Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases |
title_short | Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases |
title_sort | comprehensive insights into biological roles of rosmarinic acid: implications in diabetes, cancer and neurodegenerative diseases |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574478/ https://www.ncbi.nlm.nih.gov/pubmed/37836581 http://dx.doi.org/10.3390/nu15194297 |
work_keys_str_mv | AT azharmdkhabeer comprehensiveinsightsintobiologicalrolesofrosmarinicacidimplicationsindiabetescancerandneurodegenerativediseases AT anwarsaleha comprehensiveinsightsintobiologicalrolesofrosmarinicacidimplicationsindiabetescancerandneurodegenerativediseases AT hasangulammustafa comprehensiveinsightsintobiologicalrolesofrosmarinicacidimplicationsindiabetescancerandneurodegenerativediseases AT shamsianas comprehensiveinsightsintobiologicalrolesofrosmarinicacidimplicationsindiabetescancerandneurodegenerativediseases AT islamasimul comprehensiveinsightsintobiologicalrolesofrosmarinicacidimplicationsindiabetescancerandneurodegenerativediseases AT parvezsuhel comprehensiveinsightsintobiologicalrolesofrosmarinicacidimplicationsindiabetescancerandneurodegenerativediseases AT hassanmdimtaiyaz comprehensiveinsightsintobiologicalrolesofrosmarinicacidimplicationsindiabetescancerandneurodegenerativediseases |