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Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases

Phytochemicals are abundantly occurring natural compounds extracted from plant sources. Rosmarinic acid (RA) is an abundant phytochemical of Lamiaceae species with various therapeutic implications for human health. In recent years, natural compounds have gained significant attention as adjuvant and...

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Autores principales: Azhar, Md. Khabeer, Anwar, Saleha, Hasan, Gulam Mustafa, Shamsi, Anas, Islam, Asimul, Parvez, Suhel, Hassan, Md. Imtaiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574478/
https://www.ncbi.nlm.nih.gov/pubmed/37836581
http://dx.doi.org/10.3390/nu15194297
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author Azhar, Md. Khabeer
Anwar, Saleha
Hasan, Gulam Mustafa
Shamsi, Anas
Islam, Asimul
Parvez, Suhel
Hassan, Md. Imtaiyaz
author_facet Azhar, Md. Khabeer
Anwar, Saleha
Hasan, Gulam Mustafa
Shamsi, Anas
Islam, Asimul
Parvez, Suhel
Hassan, Md. Imtaiyaz
author_sort Azhar, Md. Khabeer
collection PubMed
description Phytochemicals are abundantly occurring natural compounds extracted from plant sources. Rosmarinic acid (RA) is an abundant phytochemical of Lamiaceae species with various therapeutic implications for human health. In recent years, natural compounds have gained significant attention as adjuvant and complementary therapies to existing medications for various diseases. RA has gained popularity due to its anti-inflammatory and antioxidant properties and its roles in various life-threatening conditions, such as cancer, neurodegeneration, diabetes, etc. The present review aims to offer a comprehensive insight into the multifaceted therapeutic properties of RA, including its potential as an anticancer agent, neuroprotective effects, and antidiabetic potential. Based on the available evidences, RA could be considered a potential dietary component for treating various diseases, including cancer, diabetes and neurodegenerative disorders.
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spelling pubmed-105744782023-10-14 Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases Azhar, Md. Khabeer Anwar, Saleha Hasan, Gulam Mustafa Shamsi, Anas Islam, Asimul Parvez, Suhel Hassan, Md. Imtaiyaz Nutrients Review Phytochemicals are abundantly occurring natural compounds extracted from plant sources. Rosmarinic acid (RA) is an abundant phytochemical of Lamiaceae species with various therapeutic implications for human health. In recent years, natural compounds have gained significant attention as adjuvant and complementary therapies to existing medications for various diseases. RA has gained popularity due to its anti-inflammatory and antioxidant properties and its roles in various life-threatening conditions, such as cancer, neurodegeneration, diabetes, etc. The present review aims to offer a comprehensive insight into the multifaceted therapeutic properties of RA, including its potential as an anticancer agent, neuroprotective effects, and antidiabetic potential. Based on the available evidences, RA could be considered a potential dietary component for treating various diseases, including cancer, diabetes and neurodegenerative disorders. MDPI 2023-10-09 /pmc/articles/PMC10574478/ /pubmed/37836581 http://dx.doi.org/10.3390/nu15194297 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Azhar, Md. Khabeer
Anwar, Saleha
Hasan, Gulam Mustafa
Shamsi, Anas
Islam, Asimul
Parvez, Suhel
Hassan, Md. Imtaiyaz
Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases
title Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases
title_full Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases
title_fullStr Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases
title_full_unstemmed Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases
title_short Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases
title_sort comprehensive insights into biological roles of rosmarinic acid: implications in diabetes, cancer and neurodegenerative diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574478/
https://www.ncbi.nlm.nih.gov/pubmed/37836581
http://dx.doi.org/10.3390/nu15194297
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