Cargando…

Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases

Phytochemicals are abundantly occurring natural compounds extracted from plant sources. Rosmarinic acid (RA) is an abundant phytochemical of Lamiaceae species with various therapeutic implications for human health. In recent years, natural compounds have gained significant attention as adjuvant and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Azhar, Md. Khabeer, Anwar, Saleha, Hasan, Gulam Mustafa, Shamsi, Anas, Islam, Asimul, Parvez, Suhel, Hassan, Md. Imtaiyaz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574478/ https://www.ncbi.nlm.nih.gov/pubmed/37836581 http://dx.doi.org/10.3390/nu15194297

Ejemplares similares

Rosmarinic Acid Exhibits Anticancer Effects via MARK4 Inhibition
por: Anwar, Saleha, et al.
Publicado: (2020)

Evaluation of Binding of Rosmarinic Acid with Human Transferrin and Its Impact on the Protein Structure: Targeting Polyphenolic Acid-Induced Protection of Neurodegenerative Disorders
por: Shamsi, Anas, et al.
Publicado: (2020)

Biophysical Insights into Implications of PEG-400 on the α-Crystallin Structure: Multispectroscopic and Microscopic Approach
por: Shamsi, Anas, et al.
Publicado: (2020)

MARK4 Inhibited by AChE Inhibitors, Donepezil and Rivastigmine Tartrate: Insights into Alzheimer’s Disease Therapy
por: Shamsi, Anas, et al.
Publicado: (2020)

Inhibiting CDK6 Activity by Quercetin Is an Attractive Strategy for Cancer Therapy
por: Yousuf, Mohd, et al.
Publicado: (2020)

Glecaprevir and Maraviroc are high-affinity inhibitors of SARS-CoV-2 main protease: possible implication in COVID-19 therapy
por: Shamsi, Anas, et al.
Publicado: (2020)

Elucidating the Interaction of Human Ferritin with Quercetin and Naringenin: Implication of Natural Products in Neurodegenerative Diseases: Molecular Docking and Dynamics Simulation Insight
por: Shamsi, Anas, et al.
Publicado: (2021)

Biophysical Elucidation of Fibrillation Inhibition by Sugar Osmolytes in α-Lactalbumin: Multispectroscopic and Molecular Docking Approaches
por: Bashir, Sania, et al.
Publicado: (2020)

MAP/Microtubule Affinity Regulating Kinase 4 Inhibitory Potential of Irisin: A New Therapeutic Strategy to Combat Cancer and Alzheimer’s Disease
por: Waseem, Rashid, et al.
Publicado: (2021)

Identification of high-affinity inhibitors of SARS-CoV-2 main protease: Towards the development of effective COVID-19 therapy
por: Mohammad, Taj, et al.
Publicado: (2020)

Potential drug targets of SARS-CoV-2: From genomics to therapeutics
por: Shamsi, Anas, et al.
Publicado: (2021)

Ellagic Acid Controls Cell Proliferation and Induces Apoptosis in Breast Cancer Cells via Inhibition of Cyclin-Dependent Kinase 6
por: Yousuf, Mohd, et al.
Publicado: (2020)

Unraveling Binding Mechanism of Alzheimer’s Drug Rivastigmine Tartrate with Human Transferrin: Molecular Docking and Multi-Spectroscopic Approach towards Neurodegenerative Diseases
por: Shamsi, Anas, et al.
Publicado: (2019)

Discovery of Hordenine as a Potential Inhibitor of Pyruvate Dehydrogenase Kinase 3: Implication in Lung Cancer Therapy
por: Anwar, Saleha, et al.
Publicado: (2020)

Therapeutic Targeting of Regulated Signaling Pathways of Non-Small Cell Lung Carcinoma
por: Hasan, Gulam Mustafa, et al.
Publicado: (2023)

Multispectroscopic and Molecular Docking Insight into Elucidating the Interaction of Irisin with Rivastigmine Tartrate: A Combinational Therapy Approach to Fight Alzheimer’s Disease
por: Waseem, Rashid, et al.
Publicado: (2021)

Elucidation of Dietary Polyphenolics as Potential Inhibitor of Microtubule Affinity Regulating Kinase 4: In silico and In vitro Studies
por: Khan, Parvez, et al.
Publicado: (2017)

Unraveling the Binding Mechanism of Alzheimer’s Drugs with Irisin: Spectroscopic, Calorimetric, and Computational Approaches
por: Waseem, Rashid, et al.
Publicado: (2022)

Mechanistic insights into MARK4 inhibition by galantamine toward therapeutic targeting of Alzheimer’s disease
por: Adnan, Mohd, et al.
Publicado: (2023)

Virtual Screening Approach to Identify High-Affinity Inhibitors of Serum and Glucocorticoid-Regulated Kinase 1 among Bioactive Natural Products: Combined Molecular Docking and Simulation Studies
por: Mohammad, Taj, et al.
Publicado: (2020)

Carbohydrate-Based Macromolecular Crowding-Induced Stabilization of Proteins: Towards Understanding the Significance of the Size of the Crowder
por: Shahid, Sumra, et al.
Publicado: (2019)

Biomedical features and therapeutic potential of rosmarinic acid
por: Noor, Saba, et al.
Publicado: (2022)

Insights into the Conserved Regulatory Mechanisms of Human and Yeast Aging
por: Dahiya, Rashmi, et al.
Publicado: (2020)

Trehalose Restrains the Fibril Load towards α-Lactalbumin Aggregation and Halts Fibrillation in a Concentration-Dependent Manner
por: Bashir, Sania, et al.
Publicado: (2021)

Identification of Thermostable Xylose Reductase from Thermothelomyces thermophilus: A Biochemical Characterization Approach to Meet Biofuel Challenges
por: Ali, Nabeel, et al.
Publicado: (2022)

Effects of Ethylene Glycol on the Structure and Stability of Myoglobin Using Spectroscopic, Interaction, and In Silico Approaches: Monomer Is Different from Those of Its Polymers
por: Parray, Zahoor Ahmad, et al.
Publicado: (2020)

Cooperative Unfolding of Residual Structure in Heat Denatured Proteins by Urea and Guanidinium Chloride
por: Singh, Ritu, et al.
Publicado: (2015)

Inhibiting Cyclin-Dependent Kinase 6 by Taurine: Implications in Anticancer Therapeutics
por: Yousuf, Mohd, et al.
Publicado: (2022)

Modulatory Role of Quercetin in Mitochondrial Dysfunction in Titanium Dioxide Nanoparticle-Induced Hepatotoxicity
por: Waseem, Mohd, et al.
Publicado: (2022)

Effect of pH on the structure and function of cyclin-dependent kinase 6
por: Yousuf, Mohd, et al.
Publicado: (2022)

Insights into the Antibacterial Activity of Prolactin-Inducible Protein against the Standard and Environmental MDR Bacterial Strains
por: Yousuf, Mohd, et al.
Publicado: (2022)

FNDC5/Irisin: Physiology and Pathophysiology
por: Waseem, Rashid, et al.
Publicado: (2022)

Therapeutic Integrity of Microbiome-based Medicines in Neurodegenerative Disorders
por: Kumar, Dhiraj, et al.
Publicado: (2022)

Insight of the Interaction between 2,4-thiazolidinedione and Human Serum Albumin: A Spectroscopic, Thermodynamic and Molecular Docking Study
por: Rahman, Safikur, et al.
Publicado: (2019)

Unraveling the Role of RNA Mediated Toxicity of C9orf72 Repeats in C9-FTD/ALS
por: Kumar, Vijay, et al.
Publicado: (2017)

Probing the Inhibition of Microtubule Affinity Regulating Kinase 4 by N-Substituted Acridones
por: Voura, Maria, et al.
Publicado: (2019)

Data on the role of accessible surface area on osmolytes-induced protein stabilization
por: Rahman, Safikur, et al.
Publicado: (2016)

Structural Features of Nucleoprotein CST/Shelterin Complex Involved in the Telomere Maintenance and Its Association with Disease Mutations
por: Amir, Mohd., et al.
Publicado: (2020)

Structure-based functional annotation of hypothetical proteins from Candida dubliniensis: a quest for potential drug targets
por: Kumar, Kundan, et al.
Publicado: (2014)

Purification and characterization of RGA2, a Rho2 GTPase-activating protein from Tinospora cordifolia
por: Amir, Mohd., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_22dhmfhe4qn47o302nr33vg5av