Cargando…
The N-Alkylation of Agelastatin A Modulates Its Chemical Reactivity
Agelastatin A is a marine alkaloid with potent biological activity. To date, at least 17 different strategies have achieved its total synthesis, along with many analogues. The present study focuses on the acidity stability of some N-methyl derivatives of agelastatin A. The study made use of chemical...
Autor principal: | D’Ambrosio, Michele |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574546/ https://www.ncbi.nlm.nih.gov/pubmed/37836663 http://dx.doi.org/10.3390/molecules28196821 |
Ejemplares similares
-
Orthogonally
Protected Diaminocyclopentenones as Synthons:
Total Synthesis of (±)-Agelastatin A
por: Gomes, Rafael F. A., et al.
Publicado: (2023) -
Formal synthesis of (−)-agelastatin A: an iron(II)-mediated cyclization strategy
por: Shigeoka, Daisuke, et al.
Publicado: (2013) -
Potent Fluorinated Agelastatin
Analogues for Chronic Lymphocytic Leukemia: Design, Synthesis, and
Pharmacokinetic Studies
por: Stout, E. Paige, et al.
Publicado: (2014) -
Regio- and diastereoselective dearomatizations of N-alkyl activated azaarenes: the maximization of the reactive sites
por: Miao, Hong-Jie, et al.
Publicado: (2019) -
General electrochemical Minisci alkylation of N-heteroarenes with alkyl halides
por: del Río-Rodríguez, Roberto, et al.
Publicado: (2022)