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Sol–Gel Technologies to Obtain Advanced Bioceramics for Dental Therapeutics

The aim of this work is to review the application of bioceramic materials in the context of current regenerative dentistry therapies, focusing on the latest advances in the synthesis of advanced materials using the sol–gel methodology. Chemical synthesis, processing and therapeutic possibilities are...

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Autores principales: Song, Xiaozhe, Segura-Egea, Juan J., Díaz-Cuenca, Aránzazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574775/
https://www.ncbi.nlm.nih.gov/pubmed/37836810
http://dx.doi.org/10.3390/molecules28196967
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author Song, Xiaozhe
Segura-Egea, Juan J.
Díaz-Cuenca, Aránzazu
author_facet Song, Xiaozhe
Segura-Egea, Juan J.
Díaz-Cuenca, Aránzazu
author_sort Song, Xiaozhe
collection PubMed
description The aim of this work is to review the application of bioceramic materials in the context of current regenerative dentistry therapies, focusing on the latest advances in the synthesis of advanced materials using the sol–gel methodology. Chemical synthesis, processing and therapeutic possibilities are discussed in a structured way, according to the three main types of ceramic materials used in regenerative dentistry: bioactive glasses and glass ceramics, calcium phosphates and calcium silicates. The morphology and chemical composition of these bioceramics play a crucial role in their biological properties and effectiveness in dental therapeutics. The goal is to understand their chemical, surface, mechanical and biological properties better and develop strategies to control their pore structure, shape, size and compositions. Over the past decades, bioceramic materials have provided excellent results in a wide variety of clinical applications related to hard tissue repair and regeneration. Characteristics, such as their similarity to the chemical composition of the mineral phase of bones and teeth, as well as the possibilities offered by the advances in nanotechnology, are driving the development of new biomimetic materials that are required in regenerative dentistry. The sol–gel technique is a method for producing synthetic bioceramics with high purity and homogeneity at the molecular scale and to control the surfaces, interfaces and porosity at the nanometric scale. The intrinsic nanoporosity of materials produced by the sol–gel technique correlates with the high specific surface area, reactivity and bioactivity of advanced bioceramics.
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spelling pubmed-105747752023-10-14 Sol–Gel Technologies to Obtain Advanced Bioceramics for Dental Therapeutics Song, Xiaozhe Segura-Egea, Juan J. Díaz-Cuenca, Aránzazu Molecules Review The aim of this work is to review the application of bioceramic materials in the context of current regenerative dentistry therapies, focusing on the latest advances in the synthesis of advanced materials using the sol–gel methodology. Chemical synthesis, processing and therapeutic possibilities are discussed in a structured way, according to the three main types of ceramic materials used in regenerative dentistry: bioactive glasses and glass ceramics, calcium phosphates and calcium silicates. The morphology and chemical composition of these bioceramics play a crucial role in their biological properties and effectiveness in dental therapeutics. The goal is to understand their chemical, surface, mechanical and biological properties better and develop strategies to control their pore structure, shape, size and compositions. Over the past decades, bioceramic materials have provided excellent results in a wide variety of clinical applications related to hard tissue repair and regeneration. Characteristics, such as their similarity to the chemical composition of the mineral phase of bones and teeth, as well as the possibilities offered by the advances in nanotechnology, are driving the development of new biomimetic materials that are required in regenerative dentistry. The sol–gel technique is a method for producing synthetic bioceramics with high purity and homogeneity at the molecular scale and to control the surfaces, interfaces and porosity at the nanometric scale. The intrinsic nanoporosity of materials produced by the sol–gel technique correlates with the high specific surface area, reactivity and bioactivity of advanced bioceramics. MDPI 2023-10-07 /pmc/articles/PMC10574775/ /pubmed/37836810 http://dx.doi.org/10.3390/molecules28196967 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Song, Xiaozhe
Segura-Egea, Juan J.
Díaz-Cuenca, Aránzazu
Sol–Gel Technologies to Obtain Advanced Bioceramics for Dental Therapeutics
title Sol–Gel Technologies to Obtain Advanced Bioceramics for Dental Therapeutics
title_full Sol–Gel Technologies to Obtain Advanced Bioceramics for Dental Therapeutics
title_fullStr Sol–Gel Technologies to Obtain Advanced Bioceramics for Dental Therapeutics
title_full_unstemmed Sol–Gel Technologies to Obtain Advanced Bioceramics for Dental Therapeutics
title_short Sol–Gel Technologies to Obtain Advanced Bioceramics for Dental Therapeutics
title_sort sol–gel technologies to obtain advanced bioceramics for dental therapeutics
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574775/
https://www.ncbi.nlm.nih.gov/pubmed/37836810
http://dx.doi.org/10.3390/molecules28196967
work_keys_str_mv AT songxiaozhe solgeltechnologiestoobtainadvancedbioceramicsfordentaltherapeutics
AT seguraegeajuanj solgeltechnologiestoobtainadvancedbioceramicsfordentaltherapeutics
AT diazcuencaaranzazu solgeltechnologiestoobtainadvancedbioceramicsfordentaltherapeutics