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Differences of Atomic-Level Interactions between Midazolam and Two CYP Isoforms 3A4 and 3A5
CYP 3A4 and CYP 3A5 are two important members of the human cytochrome P450 family. Although their overall structures are similar, the local structures of the active site are different, which directly leads to obvious individual differences in drug metabolic efficacy and toxicity. In this work, midaz...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574787/ https://www.ncbi.nlm.nih.gov/pubmed/37836743 http://dx.doi.org/10.3390/molecules28196900 |