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Myxedema Coma and the Heart: Would You Miss the Signs?

Myxedema Coma (MC) is a life-threatening medical emergency that occurs as a severe complication of untreated or poorly managed hypothyroidism. Prompt diagnosis is crucial as the condition can rapidly deteriorate and lead to life-threatening complications. Timely treatment of myxedema coma with intra...

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Autores principales: Vazquez-Fuster, Juan I, Rivera, Giovanni, Vicenty-Rivera, Sonia I, Merced, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575566/
https://www.ncbi.nlm.nih.gov/pubmed/37842478
http://dx.doi.org/10.7759/cureus.45164
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author Vazquez-Fuster, Juan I
Rivera, Giovanni
Vicenty-Rivera, Sonia I
Merced, Francisco
author_facet Vazquez-Fuster, Juan I
Rivera, Giovanni
Vicenty-Rivera, Sonia I
Merced, Francisco
author_sort Vazquez-Fuster, Juan I
collection PubMed
description Myxedema Coma (MC) is a life-threatening medical emergency that occurs as a severe complication of untreated or poorly managed hypothyroidism. Prompt diagnosis is crucial as the condition can rapidly deteriorate and lead to life-threatening complications. Timely treatment of myxedema coma with intravenous levothyroxine is the cornerstone of treatment, along with glucocorticoids to support adrenal function. This condition is associated with cardiovascular manifestations that contribute to its high mortality rate. The heart in hypothyroidism typically shows reversible dysfunction that can be corrected with hormonal supplementation, and in some cases, requires inotropic and aminergic support. This case involves a patient who was admitted to the intensive care unit with suspected MC, and necessitated life-saving hormonal and cardiovascular support to manage the condition.
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spelling pubmed-105755662023-10-14 Myxedema Coma and the Heart: Would You Miss the Signs? Vazquez-Fuster, Juan I Rivera, Giovanni Vicenty-Rivera, Sonia I Merced, Francisco Cureus Cardiology Myxedema Coma (MC) is a life-threatening medical emergency that occurs as a severe complication of untreated or poorly managed hypothyroidism. Prompt diagnosis is crucial as the condition can rapidly deteriorate and lead to life-threatening complications. Timely treatment of myxedema coma with intravenous levothyroxine is the cornerstone of treatment, along with glucocorticoids to support adrenal function. This condition is associated with cardiovascular manifestations that contribute to its high mortality rate. The heart in hypothyroidism typically shows reversible dysfunction that can be corrected with hormonal supplementation, and in some cases, requires inotropic and aminergic support. This case involves a patient who was admitted to the intensive care unit with suspected MC, and necessitated life-saving hormonal and cardiovascular support to manage the condition. Cureus 2023-09-13 /pmc/articles/PMC10575566/ /pubmed/37842478 http://dx.doi.org/10.7759/cureus.45164 Text en Copyright © 2023, Vazquez-Fuster et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Vazquez-Fuster, Juan I
Rivera, Giovanni
Vicenty-Rivera, Sonia I
Merced, Francisco
Myxedema Coma and the Heart: Would You Miss the Signs?
title Myxedema Coma and the Heart: Would You Miss the Signs?
title_full Myxedema Coma and the Heart: Would You Miss the Signs?
title_fullStr Myxedema Coma and the Heart: Would You Miss the Signs?
title_full_unstemmed Myxedema Coma and the Heart: Would You Miss the Signs?
title_short Myxedema Coma and the Heart: Would You Miss the Signs?
title_sort myxedema coma and the heart: would you miss the signs?
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575566/
https://www.ncbi.nlm.nih.gov/pubmed/37842478
http://dx.doi.org/10.7759/cureus.45164
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