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The cryo-EM structure of the human ERAD retrotranslocation complex

Endoplasmic reticulum–associated degradation (ERAD) maintains protein homeostasis by retrieving misfolded proteins from the endoplasmic reticulum (ER) lumen into the cytosol for degradation. The retrotranslocation of misfolded proteins across the ER membrane is an energy-consuming process, with the...

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Detalles Bibliográficos
Autores principales:	Rao, Bing, Wang, Qian, Yao, Deqiang, Xia, Ying, Li, Wenguo, Xie, Yuming, Li, Shaobai, Cao, Mi, Shen, Yafeng, Qin, An, Zhao, Jie, Cao, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575581/ https://www.ncbi.nlm.nih.gov/pubmed/37831771 http://dx.doi.org/10.1126/sciadv.adi5656

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