A noncanonical function of SKP1 regulates the switch between autophagy and unconventional secretion

Intracellular degradation of proteins and organelles by the autophagy-lysosome system is essential for cellular quality control and energy homeostasis. Besides degradation, endolysosomal organelles can fuse with the plasma membrane and contribute to unconventional secretion. Here, we identify a func...

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Detalles Bibliográficos
Autores principales: Li, Jie, Krause, Gregory J., Gui, Qi, Kaushik, Susmita, Rona, Gergely, Zhang, Qingyue, Liang, Feng-Xia, Dhabaria, Avantika, Anerillas, Carlos, Martindale, Jennifer L., Vasilyev, Nikita, Askenazi, Manor, Ueberheide, Beatrix, Nudler, Evgeny, Gorospe, Myriam, Cuervo, Ana Maria, Pagano, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575587/
https://www.ncbi.nlm.nih.gov/pubmed/37831778
http://dx.doi.org/10.1126/sciadv.adh1134

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