Angiopoietin-2 blockade suppresses growth of liver metastases from pancreatic neuroendocrine tumors by promoting T cell recruitment

Improving the management of metastasis in pancreatic neuroendocrine tumors (PanNETs) is critical, as nearly half of patients with PanNETs present with liver metastases, and this accounts for the majority of patient mortality. We identified angiopoietin-2 (ANGPT2) as one of the most upregulated angio...

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Detalles Bibliográficos
Autores principales: Lee, Eunhyeong, O’Keefe, Sophie, Leong, Alessandra, Park, Ha-Ram, Varadarajan, Janani, Chowdhury, Subrata, Hiner, Shannon, Kim, Sungsoo, Shiva, Anahita, Friedman, Richard A., Remotti, Helen, Fojo, Tito, Yang, Hee Won, Thurston, Gavin, Kim, Minah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575726/
https://www.ncbi.nlm.nih.gov/pubmed/37843277
http://dx.doi.org/10.1172/JCI167994

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