Patient-derived enteroids provide a platform for the development of therapeutic approaches in microvillus inclusion disease

Microvillus inclusion disease (MVID), caused by loss-of-function mutations in the motor protein myosin Vb (MYO5B), is a severe infantile disease characterized by diarrhea, malabsorption, and acid/base instability, requiring intensive parenteral support for nutritional and fluid management. Human pat...

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Detalles Bibliográficos
Autores principales: Kalashyan, Meri, Raghunathan, Krishnan, Oller, Haley, Bayer, Marie-Theres, Jimenez, Lissette, Roland, Joseph T., Kolobova, Elena, Hagen, Susan J., Goldsmith, Jeffrey D., Shub, Mitchell D., Goldenring, James R., Kaji, Izumi, Thiagarajah, Jay R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575727/
https://www.ncbi.nlm.nih.gov/pubmed/37643022
http://dx.doi.org/10.1172/JCI169234

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