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Epithelial TNF controls cell differentiation and CFTR activity to maintain intestinal mucin homeostasis

The gastrointestinal tract relies on the production, maturation, and transit of mucin to protect against pathogens and to lubricate the epithelial lining. Although the molecular and cellular mechanisms that regulate mucin production and movement are beginning to be understood, the upstream epithelia...

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Detalles Bibliográficos
Autores principales: Reyes, Efren A., Castillo-Azofeifa, David, Rispal, Jérémie, Wald, Tomas, Zwick, Rachel K., Palikuqi, Brisa, Mujukian, Angela, Rabizadeh, Shervin, Gupta, Alexander R., Gardner, James M., Boffelli, Dario, Gartner, Zev J., Klein, Ophir D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575728/
https://www.ncbi.nlm.nih.gov/pubmed/37643009
http://dx.doi.org/10.1172/JCI163591