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Epithelial TNF controls cell differentiation and CFTR activity to maintain intestinal mucin homeostasis
The gastrointestinal tract relies on the production, maturation, and transit of mucin to protect against pathogens and to lubricate the epithelial lining. Although the molecular and cellular mechanisms that regulate mucin production and movement are beginning to be understood, the upstream epithelia...
Autores principales: | Reyes, Efren A., Castillo-Azofeifa, David, Rispal, Jérémie, Wald, Tomas, Zwick, Rachel K., Palikuqi, Brisa, Mujukian, Angela, Rabizadeh, Shervin, Gupta, Alexander R., Gardner, James M., Boffelli, Dario, Gartner, Zev J., Klein, Ophir D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575728/ https://www.ncbi.nlm.nih.gov/pubmed/37643009 http://dx.doi.org/10.1172/JCI163591 |
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