Adverse outcomes in SARS-CoV-2–infected pregnant mice are gestational age–dependent and resolve with antiviral treatment

SARS-CoV-2 infection during pregnancy is associated with severe COVID-19 and adverse fetal outcomes, but the underlying mechanisms remain poorly understood. Moreover, clinical studies assessing therapeutics against SARS-CoV-2 in pregnancy are limited. To address these gaps, we developed a mouse mode...

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Detalles Bibliográficos
Autores principales: Creisher, Patrick S., Perry, Jamie L., Zhong, Weizhi, Lei, Jun, Mulka, Kathleen R., Ryan, W. Hurley, Zhou, Ruifeng, Akin, Elgin H., Liu, Anguo, Mitzner, Wayne, Burd, Irina, Pekosz, Andrew, Klein, Sabra L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575736/
https://www.ncbi.nlm.nih.gov/pubmed/37581940
http://dx.doi.org/10.1172/JCI170687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575736/
https://www.ncbi.nlm.nih.gov/pubmed/37581940
http://dx.doi.org/10.1172/JCI170687

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