Silencing circSERPINE2 restrains mesenchymal stem cell senescence via the YBX3/PCNA/p21 axis

Increasing evidence indicates that circular RNAs (circRNAs) accumulate in aging tissues and nonproliferating cells due to their high stability. However, whether upregulation of circRNA expression mediates stem cell senescence and whether circRNAs can be targeted to alleviate aging-related disorders...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Fenglei, Wang, Shan, Zeng, Chenying, Tang, Su’an, Gu, Huimin, Wang, Ziming, Li, Jinteng, Feng, Pei, Zhang, Yunhui, Wang, Peng, Wu, Yanfeng, Shen, Huiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575817/
https://www.ncbi.nlm.nih.gov/pubmed/37831180
http://dx.doi.org/10.1007/s00018-023-04975-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575817/
https://www.ncbi.nlm.nih.gov/pubmed/37831180
http://dx.doi.org/10.1007/s00018-023-04975-6

Ejemplares similares