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Silencing circSERPINE2 restrains mesenchymal stem cell senescence via the YBX3/PCNA/p21 axis
Increasing evidence indicates that circular RNAs (circRNAs) accumulate in aging tissues and nonproliferating cells due to their high stability. However, whether upregulation of circRNA expression mediates stem cell senescence and whether circRNAs can be targeted to alleviate aging-related disorders...
Autores principales: | Chen, Fenglei, Wang, Shan, Zeng, Chenying, Tang, Su’an, Gu, Huimin, Wang, Ziming, Li, Jinteng, Feng, Pei, Zhang, Yunhui, Wang, Peng, Wu, Yanfeng, Shen, Huiyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575817/ https://www.ncbi.nlm.nih.gov/pubmed/37831180 http://dx.doi.org/10.1007/s00018-023-04975-6 |
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