Cargando…

The novel sterilization device: the prototype testing

Currently, there are numerous methods that can be used to neutralize pathogens (i.e., devices, tools, or protective clothing), but the sterilizing agent must be selected so that it does not damage or change the properties of the material to which it is applied. Dry sterilization with hydrogen peroxi...

Descripción completa

Detalles Bibliográficos
Autores principales: Nowak, Robert, Wityk, Paweł, Wierzbicka-Woś, Anna, Gos, Waldemar, Kostrzewa-Nowak, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575896/
https://www.ncbi.nlm.nih.gov/pubmed/37833295
http://dx.doi.org/10.1038/s41598-023-44483-y
_version_ 1785121009170382848
author Nowak, Robert
Wityk, Paweł
Wierzbicka-Woś, Anna
Gos, Waldemar
Kostrzewa-Nowak, Dorota
author_facet Nowak, Robert
Wityk, Paweł
Wierzbicka-Woś, Anna
Gos, Waldemar
Kostrzewa-Nowak, Dorota
author_sort Nowak, Robert
collection PubMed
description Currently, there are numerous methods that can be used to neutralize pathogens (i.e., devices, tools, or protective clothing), but the sterilizing agent must be selected so that it does not damage or change the properties of the material to which it is applied. Dry sterilization with hydrogen peroxide gas (VHP) in combination with UV-C radiation is well described and effective method of sterilization. This paper presents the design, construction, and analysis of a novel model of sterilization device. Verification of the sterilization process was performed, using classical microbiological methods and flow cytometry, on samples containing Geobacillus stearothermophilus spores, Bacillus subtilis spores, Escherichia coli, and Candida albicans. Flow cytometry results were in line with the standardized microbiological tests and confirmed the effectiveness of the sterilization process. It was also determined that mobile sterilization stations represent a valuable solution when dedicated to public institutions and businesses in the tourism sector, sports & fitness industry, or other types of services, e.g., cosmetic services. A key feature of this solution is the ability to adapt the device within specific constraints to the user’s needs.
format Online
Article
Text
id pubmed-10575896
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-105758962023-10-15 The novel sterilization device: the prototype testing Nowak, Robert Wityk, Paweł Wierzbicka-Woś, Anna Gos, Waldemar Kostrzewa-Nowak, Dorota Sci Rep Article Currently, there are numerous methods that can be used to neutralize pathogens (i.e., devices, tools, or protective clothing), but the sterilizing agent must be selected so that it does not damage or change the properties of the material to which it is applied. Dry sterilization with hydrogen peroxide gas (VHP) in combination with UV-C radiation is well described and effective method of sterilization. This paper presents the design, construction, and analysis of a novel model of sterilization device. Verification of the sterilization process was performed, using classical microbiological methods and flow cytometry, on samples containing Geobacillus stearothermophilus spores, Bacillus subtilis spores, Escherichia coli, and Candida albicans. Flow cytometry results were in line with the standardized microbiological tests and confirmed the effectiveness of the sterilization process. It was also determined that mobile sterilization stations represent a valuable solution when dedicated to public institutions and businesses in the tourism sector, sports & fitness industry, or other types of services, e.g., cosmetic services. A key feature of this solution is the ability to adapt the device within specific constraints to the user’s needs. Nature Publishing Group UK 2023-10-13 /pmc/articles/PMC10575896/ /pubmed/37833295 http://dx.doi.org/10.1038/s41598-023-44483-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Nowak, Robert
Wityk, Paweł
Wierzbicka-Woś, Anna
Gos, Waldemar
Kostrzewa-Nowak, Dorota
The novel sterilization device: the prototype testing
title The novel sterilization device: the prototype testing
title_full The novel sterilization device: the prototype testing
title_fullStr The novel sterilization device: the prototype testing
title_full_unstemmed The novel sterilization device: the prototype testing
title_short The novel sterilization device: the prototype testing
title_sort novel sterilization device: the prototype testing
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575896/
https://www.ncbi.nlm.nih.gov/pubmed/37833295
http://dx.doi.org/10.1038/s41598-023-44483-y
work_keys_str_mv AT nowakrobert thenovelsterilizationdevicetheprototypetesting
AT witykpaweł thenovelsterilizationdevicetheprototypetesting
AT wierzbickawosanna thenovelsterilizationdevicetheprototypetesting
AT goswaldemar thenovelsterilizationdevicetheprototypetesting
AT kostrzewanowakdorota thenovelsterilizationdevicetheprototypetesting
AT nowakrobert novelsterilizationdevicetheprototypetesting
AT witykpaweł novelsterilizationdevicetheprototypetesting
AT wierzbickawosanna novelsterilizationdevicetheprototypetesting
AT goswaldemar novelsterilizationdevicetheprototypetesting
AT kostrzewanowakdorota novelsterilizationdevicetheprototypetesting